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Disc Medicine

168 hedge funds and large institutions have $2.26B invested in Disc Medicine in 2025 Q3 according to their latest regulatory filings, with 26 funds opening new positions, 61 increasing their positions, 45 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

254% more call options, than puts

Call options by funds: $3.08M | Put options by funds: $871K

189% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 9

36% more repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 45

25% more capital invested

Capital invested by funds: $1.8B → $2.26B (+$454M)

11% more funds holding

Funds holding: 151168 (+17)

0.06% more ownership

Funds ownership: 98.37%98.43% (+0.06%)

22% less funds holding in top 10

Funds holding in top 10: 97 (-2)

Holders
168
Holders Change
+17
Holders Change %
+11.26%
% of All Funds
2.2%
Holding in Top 10
7
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-22.22%
% of All Funds
0.09%
New
26
Increased
61
Reduced
45
Closed
9
Calls
$3.08M
Puts
$871K
Net Calls
+$2.21M
Net Calls Change
-$20.1M
Name Holding Trade Value Shares
Change
Change in
Stake
KCM
101
Kennedy Capital Management
Missouri
$597K +$537K +9,028 New
CSS
102
Cubist Systematic Strategies
Connecticut
$576K +$518K +8,714 New
PA
103
Profund Advisors
Maryland
$536K +$83.5K +1,404 +21%
SG Americas Securities
104
SG Americas Securities
New York
$533K +$480K +8,064 New
IIM
105
INTECH Investment Management
Florida
$529K -$251K -4,216 -34%
CUAMC
106
China Universal Asset Management Company
China
$469K +$8.21K +138 +2%
Renaissance Technologies
107
Renaissance Technologies
New York
$449K -$5.33M -89,620 -93%
ASRS
108
Arizona State Retirement System
Arizona
$440K +$7.14K +120 +2%
PFSRSONJ
109
Police & Firemen's Retirement System of New Jersey
New Jersey
$430K +$60.1K +1,011 +18%
Verition Fund Management
110
Verition Fund Management
Connecticut
$405K +$365K +6,133 New
DnB Asset Management
111
DnB Asset Management
Norway
$365K +$55.9K +939 +20%
Teacher Retirement System of Texas
112
Teacher Retirement System of Texas
Texas
$363K -$31.5K -530 -9%
Squarepoint
113
Squarepoint
New York
$355K +$320K +5,377 New
CCIA
114
Campbell & Co Investment Adviser
Maryland
$350K +$315K +5,290 New
ProShare Advisors
115
ProShare Advisors
Maryland
$343K -$68.8K -1,157 -18%
HP
116
HealthInvest Partners
Sweden
$321K +$1.25M +21,038 +85%
KK
117
KLP Kapitalforvaltning
Norway
$304K
VOYA Investment Management
118
VOYA Investment Management
Georgia
$282K -$144K -2,429 -36%
FT
119
Fiduciary Trust
Massachusetts
$268K
Citigroup
120
Citigroup
New York
$267K -$718K -12,064 -75%
BPC
121
Bryce Point Capital
New York
$259K +$233K +3,912 New
SPS
122
Susquehanna Portfolio Strategies
Pennsylvania
$247K +$222K +3,733 New
Pictet Asset Management
123
Pictet Asset Management
Switzerland
$235K +$212K +3,563 New
Zurich Cantonal Bank
124
Zurich Cantonal Bank
Switzerland
$197K -$3.51K -59 -2%
Russell Investments Group
125
Russell Investments Group
United Kingdom
$161K +$144K +2,422 +15,138%

IRON Hedge Fund Activity: Q3 2025 in Review

168 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q3 2025, worth a combined $2.26B — up 25% from $1.8B a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new IRON positions and 9 closed out — a net gain of 17 holders — while 61 added to existing stakes and 45 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $101M. The largest seller was Janus Henderson Group, cutting an estimated $70.9M.

  • 168 institutional investors held Disc Medicine (IRON) as of Q3 2025, up from 151 in Q2 2025.
  • Funds reported $2.26B of Disc Medicine stock for Q3 2025, up 25% quarter-over-quarter.
  • 26 funds opened new Disc Medicine positions in Q3 2025 and 9 closed out, a net change of +17 holders.
  • The largest Disc Medicine buyer in Q3 2025 was Fidelity Investments, an estimated $101M added.
  • The largest Disc Medicine seller in Q3 2025 was Janus Henderson Group, an estimated $70.9M sold.

Based on aggregated 13F filings for Q3 2025.