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Disc Medicine

168 hedge funds and large institutions have $2.26B invested in Disc Medicine in 2025 Q3 according to their latest regulatory filings, with 26 funds opening new positions, 61 increasing their positions, 45 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

254% more call options, than puts

Call options by funds: $3.08M | Put options by funds: $871K

189% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 9

36% more repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 45

25% more capital invested

Capital invested by funds: $1.8B → $2.26B (+$454M)

11% more funds holding

Funds holding: 151168 (+17)

0.06% more ownership

Funds ownership: 98.37%98.43% (+0.06%)

22% less funds holding in top 10

Funds holding in top 10: 97 (-2)

Holders
168
Holders Change
+17
Holders Change %
+11.26%
% of All Funds
2.2%
Holding in Top 10
7
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-22.22%
% of All Funds
0.09%
New
26
Increased
61
Reduced
45
Closed
9
Calls
$3.08M
Puts
$871K
Net Calls
+$2.21M
Net Calls Change
-$20.1M
Name Holding Trade Value Shares
Change
Change in
Stake
AllianceBernstein
76
AllianceBernstein
Tennessee
$1.62M +$23.8K +400 +2%
California State Teachers Retirement System (CalSTRS)
77
California State Teachers Retirement System (CalSTRS)
California
$1.46M +$110K +1,843 +9%
New York State Common Retirement Fund
78
New York State Common Retirement Fund
New York
$1.42M +$276K +4,638 +28%
Invesco
79
Invesco
Georgia
$1.42M +$275K +4,626 +28%
Jane Street
80
Jane Street
New York
$1.41M +$1.27M +21,274 New
Deutsche Bank
81
Deutsche Bank
Germany
$1.25M +$129K +2,169 +13%
PCM
82
Prelude Capital Management
New York
$1.2M
Bank of Montreal
83
Bank of Montreal
Ontario, Canada
$1.18M +$404K +6,797 +62%
AA
84
ALPS Advisors
Colorado
$1.11M -$109K -1,834 -10%
Royal Bank of Canada
85
Royal Bank of Canada
Ontario, Canada
$1.1M -$351K -5,903 -26%
Walleye Capital
86
Walleye Capital
New York
$968K +$34.8K +585 +4%
Marshall Wace
87
Marshall Wace
United Kingdom
$925K +$833K +14,001 New
AQR Capital Management
88
AQR Capital Management
Connecticut
$924K +$19.6K +329 +2%
MIM
89
MetLife Investment Management
New Jersey
$920K -$55.4K -932 -6%
FAM
90
Fred Alger Management
New York
$907K +$817K +13,726 New
SI
91
Sofinnova Investments
California
$896K +$371K +6,241 +85%
TRSOTSOK
92
Teachers Retirement System of the State of Kentucky
Kentucky
$849K
Mirae Asset Global ETFs Holdings
93
Mirae Asset Global ETFs Holdings
Hong Kong
$834K -$142K -2,395 -16%
State of Wisconsin Investment Board
94
State of Wisconsin Investment Board
Wisconsin
$818K -$30.7K -516 -4%
Universal-Beteiligungs- und Servicegesellschaft
95
Universal-Beteiligungs- und Servicegesellschaft
Germany
$756K +$242K +4,062 +55%
LCM
96
Legato Capital Management
California
$746K +$241K +4,059 +56%
LPC
97
Lion Point Capital
New York
$700K
Assenagon Asset Management
98
Assenagon Asset Management
Luxembourg
$689K +$621K +10,433 New
Point72 Asset Management
99
Point72 Asset Management
Connecticut
$610K +$549K +9,226 New
State Board of Administration of Florida Retirement System
100
State Board of Administration of Florida Retirement System
Florida
$603K

IRON Hedge Fund Activity: Q3 2025 in Review

168 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q3 2025, worth a combined $2.26B — up 25% from $1.8B a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new IRON positions and 9 closed out — a net gain of 17 holders — while 61 added to existing stakes and 45 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $101M. The largest seller was Janus Henderson Group, cutting an estimated $70.9M.

  • 168 institutional investors held Disc Medicine (IRON) as of Q3 2025, up from 151 in Q2 2025.
  • Funds reported $2.26B of Disc Medicine stock for Q3 2025, up 25% quarter-over-quarter.
  • 26 funds opened new Disc Medicine positions in Q3 2025 and 9 closed out, a net change of +17 holders.
  • The largest Disc Medicine buyer in Q3 2025 was Fidelity Investments, an estimated $101M added.
  • The largest Disc Medicine seller in Q3 2025 was Janus Henderson Group, an estimated $70.9M sold.

Based on aggregated 13F filings for Q3 2025.