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Disc Medicine

196 hedge funds and large institutions have $3.04B invested in Disc Medicine in 2025 Q4 according to their latest regulatory filings, with 42 funds opening new positions, 86 increasing their positions, 48 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

250% more first-time investments, than exits

New positions opened: 42 | Existing positions closed: 12

79% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 48

57% more funds holding in top 10

Funds holding in top 10: 711 (+4)

35% more capital invested

Capital invested by funds: $2.26B → $3.04B (+$782M)

17% more funds holding

Funds holding: 168196 (+28)

3% more ownership

Funds ownership: 98.43%101.43% (+3%)

71% less call options, than puts

Call options by funds: $2.76M | Put options by funds: $9.43M

Holders
196
Holders Change
+28
Holders Change %
+16.67%
% of All Funds
2.38%
Holding in Top 10
11
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+57.14%
% of All Funds
0.13%
New
42
Increased
86
Reduced
48
Closed
12
Calls
$2.76M
Puts
$9.43M
Net Calls
-$6.66M
Net Calls Change
-$8.87M
Name Holding Trade Value Shares
Change
Change in
Stake
Citadel Advisors
51
Citadel Advisors
Florida
$7.97M +$4.22M +50,001 +99%
Barclays
52
Barclays
United Kingdom
$7.91M -$641K -7,591 -7%
DnB Asset Management
53
DnB Asset Management
Norway
$6.69M +$6.65M +78,733 +1,426%
Ameriprise
54
Ameriprise
Minnesota
$6.59M +$730K +8,634 +12%
Raymond James Financial
55
Raymond James Financial
Florida
$6.18M -$5.17M -61,205 -43%
Victory Capital Management
56
Victory Capital Management
Texas
$6.06M -$6.21M -73,526 -49%
Morgan Stanley
57
Morgan Stanley
New York
$5.94M +$1.58M +18,751 +33%
PSC
58
Patient Square Capital
California
$5.88M
TD Asset Management
59
TD Asset Management
Ontario, Canada
$5.53M +$878K +10,386 +18%
Bank of New York Mellon
60
Bank of New York Mellon
New York
$5.38M +$246K +2,907 +4%
IGAM
61
iA Global Asset Management
Quebec, Canada
$5.28M +$77.6K +918 +1%
Tudor Investment Corp
62
Tudor Investment Corp
Connecticut
$5.25M +$5.59M +66,125 New
Verition Fund Management
63
Verition Fund Management
Connecticut
$5.05M +$4.85M +57,402 +936%
Renaissance Technologies
64
Renaissance Technologies
New York
$4.99M +$4.73M +56,020 +824%
Invesco
65
Invesco
Georgia
$4.85M +$3.35M +39,627 +185%
KCA
66
KVP Capital Advisors
California
$4.63M +$4.92M +58,250 New
ECM
67
ExodusPoint Capital Management
New York
$4.62M +$4.92M +58,211 New
Lazard Asset Management
68
Lazard Asset Management
New York
$4.61M +$4.91M +58,053 New
SCM
69
Sio Capital Management
New York
$4.57M -$19.2M -227,201 -80%
Manulife (Manufacturers Life Insurance)
70
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$4.07M +$417K +4,933 +10%
Alyeska Investment Group
71
Alyeska Investment Group
Illinois
$3.97M +$4.22M +50,000 New
BGM
72
Burkehill Global Management
New York
$3.97M +$4.22M +50,000 New
BHCM
73
Brevan Howard Capital Management
Jersey
$3.89M +$4.2M +49,713 New
Schroder Investment Management Group
74
Schroder Investment Management Group
United Kingdom
$3.85M -$1.44M -17,093 -25%
N
75
Nuveen
North Carolina
$3.85M +$65.7K +777 +2%