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Disc Medicine

168 hedge funds and large institutions have $2.26B invested in Disc Medicine in 2025 Q3 according to their latest regulatory filings, with 26 funds opening new positions, 61 increasing their positions, 45 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

254% more call options, than puts

Call options by funds: $3.08M | Put options by funds: $871K

189% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 9

36% more repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 45

25% more capital invested

Capital invested by funds: $1.8B → $2.26B (+$454M)

11% more funds holding

Funds holding: 151168 (+17)

0.06% more ownership

Funds ownership: 98.37%98.43% (+0.06%)

22% less funds holding in top 10

Funds holding in top 10: 97 (-2)

Holders
168
Holders Change
+17
Holders Change %
+11.26%
% of All Funds
2.2%
Holding in Top 10
7
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-22.22%
% of All Funds
0.09%
New
26
Increased
61
Reduced
45
Closed
9
Calls
$3.08M
Puts
$871K
Net Calls
+$2.21M
Net Calls Change
-$20.1M
Name Holding Trade Value Shares
Change
Change in
Stake
ZP
51
Zimmer Partners
New York
$5.96M
NIP
52
Nicholas Investment Partners
California
$5.82M +$2M +33,558 +62%
Ameriprise
53
Ameriprise
Minnesota
$4.91M -$2.81M -47,170 -39%
PSC
54
Patient Square Capital
California
$4.89M
Schroder Investment Management Group
55
Schroder Investment Management Group
United Kingdom
$4.37M -$907K -15,255 -19%
IGAM
56
iA Global Asset Management
Quebec, Canada
$4.33M +$3.88M +65,190 +20,245%
Bank of New York Mellon
57
Bank of New York Mellon
New York
$4.28M -$399K -6,702 -9%
EAM
58
Exome Asset Management
New York
$4.05M
TD Asset Management
59
TD Asset Management
Ontario, Canada
$3.92M +$369K +6,200 +12%
Morgan Stanley
60
Morgan Stanley
New York
$3.71M -$3.25M -54,604 -49%
Citadel Advisors
61
Citadel Advisors
Florida
$3.33M +$3M +50,394 New
N
62
Nuveen
North Carolina
$3.15M -$153K -2,576 -5%
Manulife (Manufacturers Life Insurance)
63
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$3.14M -$253K -4,259 -8%
Swiss National Bank
64
Swiss National Bank
Switzerland
$2.88M +$41.6K +700 +2%
YIH
65
Y-Intercept (HK)
Hong Kong
$2.86M +$2.02M +33,905 +361%
BNP Paribas Financial Markets
66
BNP Paribas Financial Markets
France
$2.49M +$1.96M +32,907 +700%
Rafferty Asset Management
67
Rafferty Asset Management
New York
$2.46M +$346K +5,813 +18%
RhumbLine Advisers
68
RhumbLine Advisers
Massachusetts
$2.28M -$75.3K -1,265 -4%
Susquehanna International Group
69
Susquehanna International Group
Pennsylvania
$2.16M -$2.58M -43,380 -57%
PHS
70
PFM Health Sciences
California
$2.15M +$104K +1,740 +6%
Aberdeen Group
71
Aberdeen Group
United Kingdom
$2.12M
American Century Companies
72
American Century Companies
Missouri
$1.85M +$1.66M +27,938 New
Wells Fargo
73
Wells Fargo
California
$1.79M +$273K +4,594 +20%
Legal & General Group
74
Legal & General Group
United Kingdom
$1.66M +$62.5K +1,050 +4%
PNC Financial Services Group
75
PNC Financial Services Group
Pennsylvania
$1.66M +$357 +6 +0%

IRON Hedge Fund Activity: Q3 2025 in Review

168 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q3 2025, worth a combined $2.26B — up 25% from $1.8B a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new IRON positions and 9 closed out — a net gain of 17 holders — while 61 added to existing stakes and 45 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $101M. The largest seller was Janus Henderson Group, cutting an estimated $70.9M.

  • 168 institutional investors held Disc Medicine (IRON) as of Q3 2025, up from 151 in Q2 2025.
  • Funds reported $2.26B of Disc Medicine stock for Q3 2025, up 25% quarter-over-quarter.
  • 26 funds opened new Disc Medicine positions in Q3 2025 and 9 closed out, a net change of +17 holders.
  • The largest Disc Medicine buyer in Q3 2025 was Fidelity Investments, an estimated $101M added.
  • The largest Disc Medicine seller in Q3 2025 was Janus Henderson Group, an estimated $70.9M sold.

Based on aggregated 13F filings for Q3 2025.