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Disc Medicine

196 hedge funds and large institutions have $3.04B invested in Disc Medicine in 2025 Q4 according to their latest regulatory filings, with 42 funds opening new positions, 86 increasing their positions, 48 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

250% more first-time investments, than exits

New positions opened: 42 | Existing positions closed: 12

79% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 48

57% more funds holding in top 10

Funds holding in top 10: 711 (+4)

35% more capital invested

Capital invested by funds: $2.26B → $3.04B (+$782M)

17% more funds holding

Funds holding: 168196 (+28)

3% more ownership

Funds ownership: 98.43%101.43% (+3%)

71% less call options, than puts

Call options by funds: $2.76M | Put options by funds: $9.43M

Holders
196
Holders Change
+28
Holders Change %
+16.67%
% of All Funds
2.38%
Holding in Top 10
11
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+57.14%
% of All Funds
0.13%
New
42
Increased
86
Reduced
48
Closed
12
Calls
$2.76M
Puts
$9.43M
Net Calls
-$6.66M
Net Calls Change
-$8.87M
Name Holding Trade Value Shares
Change
Change in
Stake
Pictet Asset Management
26
Pictet Asset Management
Switzerland
$31.3M +$33M +390,811 +10,969%
Assenagon Asset Management
27
Assenagon Asset Management
Luxembourg
$28.4M +$29.4M +347,403 +3,330%
BBA
28
Baker Bros. Advisors
New York
$26.8M
PAI
29
Palo Alto Investors
California
$25.2M +$7.87M +93,156 +42%
FCMV
30
Foresite Capital Management V
California
$23.7M
SVCM
31
Saturn V Capital Management
Texas
$23.7M -$3.59M -42,468 -12%
Loomis, Sayles & Company
32
Loomis, Sayles & Company
Massachusetts
$22.4M +$23.9M +282,409 New
GPP
33
Great Point Partners
Connecticut
$19.9M +$21.1M +250,000 New
Charles Schwab
34
Charles Schwab
California
$19.6M +$1.72M +20,384 +9%
Aberdeen Group
35
Aberdeen Group
United Kingdom
$18.6M +$17.1M +202,297 +631%
Northern Trust
36
Northern Trust
Illinois
$18.1M +$725K +8,581 +4%
Dimensional Fund Advisors
37
Dimensional Fund Advisors
Texas
$17.7M -$579K -6,848 -3%
Balyasny Asset Management
38
Balyasny Asset Management
Illinois
$17.6M -$9.83M -116,340 -34%
OM
39
Opaleye Management
Massachusetts
$15.9M +$526K +6,227 +3%
TCM
40
TimesSquare Capital Management
New York
$14.9M +$474K +5,607 +3%
Millennium Management
41
Millennium Management
New York
$14.7M +$2.01M +23,779 +15%
Ensign Peak Advisors
42
Ensign Peak Advisors
Utah
$14.1M
FTM
43
First Turn Management
California
$12.2M -$20.7M -244,487 -61%
Bank of America
44
Bank of America
North Carolina
$10.8M -$2.13M -25,198 -16%
NCM
45
Nantahala Capital Management
Connecticut
$10.5M -$13.1M -155,000 -54%
BNP Paribas Financial Markets
46
BNP Paribas Financial Markets
France
$9.7M +$7.14M +84,543 +225%
UBS Group
47
UBS Group
Switzerland
$9.22M -$4.69M -55,511 -32%
UBS AM
48
UBS AM
Illinois
$9.08M +$1.94M +22,971 +25%
SI
49
Sofinnova Investments
California
$8.82M +$8.23M +97,457 +719%
CCM
50
Catalio Capital Management
New York
$8.77M -$8.97M -106,100 -49%