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Disc Medicine

168 hedge funds and large institutions have $2.26B invested in Disc Medicine in 2025 Q3 according to their latest regulatory filings, with 26 funds opening new positions, 61 increasing their positions, 45 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

254% more call options, than puts

Call options by funds: $3.08M | Put options by funds: $871K

189% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 9

36% more repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 45

25% more capital invested

Capital invested by funds: $1.8B → $2.26B (+$454M)

11% more funds holding

Funds holding: 151168 (+17)

0.06% more ownership

Funds ownership: 98.37%98.43% (+0.06%)

22% less funds holding in top 10

Funds holding in top 10: 97 (-2)

Holders
168
Holders Change
+17
Holders Change %
+11.26%
% of All Funds
2.2%
Holding in Top 10
7
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-22.22%
% of All Funds
0.09%
New
26
Increased
61
Reduced
45
Closed
9
Calls
$3.08M
Puts
$871K
Net Calls
+$2.21M
Net Calls Change
-$20.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Balyasny Asset Management
26
Balyasny Asset Management
Illinois
$22.3M +$20.1M +338,101 New
BBA
27
Baker Bros. Advisors
New York
$22.3M
EAM
28
Eventide Asset Management
Massachusetts
$20.4M +$773 +13 +0%
FCMV
29
Foresite Capital Management V
California
$19.8M
NCM
30
Nantahala Capital Management
Connecticut
$19M
SCM
31
Sio Capital Management
New York
$18.8M
PBA
32
Paradigm Biocapital Advisors
New York
$16.4M -$57.3M -963,255 -80%
FLAM
33
First Light Asset Management
Minnesota
$15.3M +$13.8M +231,186 New
Dimensional Fund Advisors
34
Dimensional Fund Advisors
Texas
$15.2M +$2.23M +37,567 +19%
Charles Schwab
35
Charles Schwab
California
$15M +$1.33M +22,414 +11%
PAI
36
Palo Alto Investors
California
$14.8M +$4.68M +78,609 +54%
Northern Trust
37
Northern Trust
Illinois
$14.5M +$23.4K +394 +0.2%
CCM
38
Catalio Capital Management
New York
$14.3M +$11.1M +185,866 +606%
OM
39
Opaleye Management
Massachusetts
$12.8M +$438K +7,355 +4%
TCM
40
TimesSquare Capital Management
New York
$12M +$10.8M +182,170 New
Ensign Peak Advisors
41
Ensign Peak Advisors
Utah
$11.7M +$2.11M +35,505 +25%
UBS Group
42
UBS Group
Switzerland
$11.3M +$1.55M +26,074 +18%
Bank of America
43
Bank of America
North Carolina
$10.7M -$454K -7,638 -5%
Millennium Management
44
Millennium Management
New York
$10.6M +$8.29M +139,407 +646%
Victory Capital Management
45
Victory Capital Management
Texas
$9.9M -$2.85M -47,960 -24%
Raymond James Financial
46
Raymond James Financial
Florida
$9.35M +$3.27M +54,992 +64%
Barclays
47
Barclays
United Kingdom
$7.08M +$1.23M +20,645 +24%
BOCH
48
Blue Owl Capital Holdings
New York
$6.76M -$1.19M -20,000 -16%
Hudson Bay Capital Management
49
Hudson Bay Capital Management
Connecticut
$6.75M +$6.08M +102,185 New
UBS AM
50
UBS AM
Illinois
$6.04M -$1.8M -30,204 -25%

IRON Hedge Fund Activity: Q3 2025 in Review

168 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q3 2025, worth a combined $2.26B — up 25% from $1.8B a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new IRON positions and 9 closed out — a net gain of 17 holders — while 61 added to existing stakes and 45 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $101M. The largest seller was Janus Henderson Group, cutting an estimated $70.9M.

  • 168 institutional investors held Disc Medicine (IRON) as of Q3 2025, up from 151 in Q2 2025.
  • Funds reported $2.26B of Disc Medicine stock for Q3 2025, up 25% quarter-over-quarter.
  • 26 funds opened new Disc Medicine positions in Q3 2025 and 9 closed out, a net change of +17 holders.
  • The largest Disc Medicine buyer in Q3 2025 was Fidelity Investments, an estimated $101M added.
  • The largest Disc Medicine seller in Q3 2025 was Janus Henderson Group, an estimated $70.9M sold.

Based on aggregated 13F filings for Q3 2025.