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Ionis Pharmaceuticals

354 hedge funds and large institutions have $5.61B invested in Ionis Pharmaceuticals in 2024 Q4 according to their latest regulatory filings, with 58 funds opening new positions, 119 increasing their positions, 120 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

16% more first-time investments, than exits

New positions opened: 58 | Existing positions closed: 50

1.72% more ownership

Funds ownership: 99.9%101.62% (+1.7%)

0% more funds holding

Funds holding: 353354 (+1)

1% less repeat investments, than reductions

Existing positions increased: 119 | Existing positions reduced: 120

11% less capital invested

Capital invested by funds: $6.3B → $5.61B (-$692M)

15% less call options, than puts

Call options by funds: $26.1M | Put options by funds: $30.5M

Holders
354
Holders Change
+1
Holders Change %
+0.28%
% of All Funds
4.66%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
58
Increased
119
Reduced
120
Closed
50
Calls
$26.1M
Puts
$30.5M
Net Calls
-$4.46M
Net Calls Change
-$17.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Zurich Cantonal Bank
151
Zurich Cantonal Bank
Switzerland
$1.27M +$202K +5,400 +17%
GD
152
Grandfield & Dodd
New York
$1.25M +$40.1K +1,074 +3%
GC
153
Guggenheim Capital
Illinois
$1.24M -$66.8K -1,786 -5%
CUAMC
154
China Universal Asset Management Company
China
$1.17M +$200K +5,359 +19%
KK
155
KLP Kapitalforvaltning
Norway
$1.02M +$1.09M +29,200 New
PP
156
PDT Partners
New York
$1.01M +$583K +15,594 +116%
Mariner
157
Mariner
Kansas
$967K +$169K +4,534 +20%
BCM
158
BlueCrest Capital Management
Jersey
$916K +$979K +26,200 New
Susquehanna International Group
159
Susquehanna International Group
Pennsylvania
$911K -$1.17M -31,175 -54%
Pathstone Holdings
160
Pathstone Holdings
New Jersey
$911K -$65.4K -1,749 -6%
XT
161
XTX Topco
Cayman Islands
$887K +$320K +8,557 +51%
TRSOTSOK
162
Teachers Retirement System of the State of Kentucky
Kentucky
$842K
CHP
163
Castle Hook Partners
New York
$837K
SG Americas Securities
164
SG Americas Securities
New York
$836K +$617K +16,508 +223%
D.E. Shaw & Co
165
D.E. Shaw & Co
New York
$808K -$4.56M -121,968 -84%
JFG
166
Jefferies Financial Group
New York
$782K -$1.14M -30,400 -58%
Commonwealth Equity Services
167
Commonwealth Equity Services
Massachusetts
$763K +$13.9K +373 +2%
BC
168
Bridgefront Capital
Texas
$762K +$396K +10,606 +95%
BHCM
169
Brevan Howard Capital Management
Jersey
$747K -$266K -7,113 -25%
Canada Pension Plan Investment Board
170
Canada Pension Plan Investment Board
Ontario, Canada
$696K +$325K +8,700 +78%
NIM
171
Nicollet Investment Management
Minnesota
$692K -$23K -616 -3%
X
172
Xponance
Pennsylvania
$676K +$11.9K +318 +2%
Victory Capital Management
173
Victory Capital Management
Texas
$629K -$12.9K -346 -2%
AIM
174
Aigen Investment Management
New York
$620K +$228K +6,111 +53%
TI
175
Tidal Investments
Wisconsin
$609K -$56.1K -1,501 -8%

IONS Hedge Fund Activity: Q4 2024 in Review

354 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2024, worth a combined $5.61B — down 11% from $6.3B a quarter earlier.

Buyers outnumbered sellers: 58 funds opened new IONS positions and 50 closed out — a net gain of 8 holders — while 119 added to existing stakes and 120 trimmed.

The largest buyer was Capital World Investors, adding an estimated $136M. The largest seller was Artisan Partners, cutting an estimated $74.3M.

  • 354 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2024, up from 353 in Q3 2024.
  • Funds reported $5.61B of Ionis Pharmaceuticals stock for Q4 2024, down 11% quarter-over-quarter.
  • 58 funds opened new Ionis Pharmaceuticals positions in Q4 2024 and 50 closed out, a net change of +8 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2024 was Capital World Investors, an estimated $136M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2024 was Artisan Partners, an estimated $74.3M sold.

Based on aggregated 13F filings for Q4 2024.