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XTX Topco’s Ionis Pharmaceuticals IONS Stock Holding History

XTX Topco’s Portfolio IONS Stock Details IONS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$6.05M Buy
80,519
+63,602
+376% +$5.02M 0.11% 201
2025
Q4 		$1.34M Buy
+16,917
New +$1.27M 0.04% 823
2025
Q2 		– Sell
-12,404
Closed -$374K – 2748
2025
Q1 		$374K Sell
12,404
-12,958
-51% -$424K 0.02% 1239
2024
Q4 		$887K Buy
25,362
+8,557
+51% +$320K 0.07% 370
2024
Q3 		$673K Buy
+16,805
New +$782K 0.05% 621
2024
Q2 		– Sell
-8,585
Closed -$372K – 2144
2024
Q1 		$372K Buy
+8,585
New +$409K 0.05% 666
2023
Q4 		– Sell
-16,352
Closed -$742K – 1830
2023
Q3 		$742K Buy
+16,352
New +$675K 0.13% 198

Other funds holding IONS

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Capital World Investors
Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

XTX Topco's IONS Position: Q1 2026 in Review

XTX Topco increased its Ionis Pharmaceuticals (IONS) stake by 376% in Q1 2026, buying an estimated $5.02M and bringing the position to 80,519 shares worth $6.05M. The position accounts for 0.11% of the portfolio, ranked #201.

XTX Topco first reported a position in IONS in Q3 2023 and has held it in 7 quarters since. 493 funds tracked by Wall St. Rank hold IONS as of Q1 2026.

  • XTX Topco held 80,519 shares of Ionis Pharmaceuticals worth $6.05M as of Q1 2026.
  • XTX Topco bought 63,602 Ionis Pharmaceuticals shares in Q1 2026, an estimated $5.02M.
  • Ionis Pharmaceuticals made up 0.11% of XTX Topco's portfolio in Q1 2026, its #201 holding.
  • XTX Topco first reported a position in Ionis Pharmaceuticals in Q3 2023 and has held it in 7 quarters since.
  • 493 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q1 2026.

Based on XTX Topco's 13F filing for Q1 2026, filed 15 May 2026.