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Ionis Pharmaceuticals
IONS

Overview Fund Activity

314 hedge funds and large institutions have $4.23B invested in Ionis Pharmaceuticals in 2016 Q1 according to their latest regulatory filings, with 40 funds opening new positions, 122 increasing their positions, 85 reducing their positions, and 58 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
314
Holders Change
-20
Holders Change %
-5.99%
% of All Funds
8.38%
Holding in Top 10
5
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-28.57%
% of All Funds
0.13%
New
40
Increased
122
Reduced
85
Closed
58
Calls
$35M
Puts
$41.2M
Net Calls
-$6.25M
Net Calls Change
+$2.84M

Top Buyers

1
ClearBridge Investments
1
ClearBridge Investments
New York
$451M
2
Millennium Management
2
Millennium Management
New York
$43.7M
3
Invesco
3
Invesco
Georgia
$26.5M
4
State Street
4
State Street
Massachusetts
$123M
5
AGA
5
Altrinsic Global Advisors
Connecticut
$25M

Top Sellers

1
First Trust Advisors
1
First Trust Advisors
Illinois
$44.2M
2
Stifel Financial
2
Stifel Financial
Missouri
$0
3
Goldman Sachs
3
Goldman Sachs
New York
$27.4M
4
Two Sigma Investments
4
Two Sigma Investments
New York
$0
5
EAM
5
EverPoint Asset Management
Connecticut
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
HSBC Holdings
151
HSBC Holdings
United Kingdom
$723K -$84.2K -2,079 -10%
Jane Street
152
Jane Street
New York
$720K -$890K -21,998 -55%
SG Americas Securities
153
SG Americas Securities
New York
$697K +$113K +2,789 +19%
JG
154
Jefferies Group
New York
$693K -$630K -15,547 -48%
HK
155
Horizon Kinetics
New York
$688K – – –
Bank of Montreal
156
Bank of Montreal
Ontario, Canada
$682K -$11.7K -289 -2%
Neuberger Berman Group
157
Neuberger Berman Group
New York
$671K -$8.14K -201 -1%
Mitsubishi UFJ Asset Management
158
Mitsubishi UFJ Asset Management
Japan
$671K +$80.5K +1,990 +14%
SIA
159
Starfire Investment Advisers
Michigan
$670K – – –
PCM
160
Perkins Capital Management
Minnesota
$622K -$184K -4,550 -23%
BNP Paribas Financial Markets
161
BNP Paribas Financial Markets
France
$620K -$587K -14,490 -49%
FSA
162
Franklin Street Advisors
North Carolina
$616K -$138K -3,400 -18%
AB
163
Amalgamated Bank
New York
$574K +$44.9K +1,108 +8%
AT
164
Arden Trust
Delaware
$572K +$156K +3,848 +38%
Zurich Cantonal Bank
165
Zurich Cantonal Bank
Switzerland
$560K – – –
MJP
166
Michael J. Puzo
$557K +$10.1K +250 +2%
VKH
167
Virtu KCG Holdings
New York
$547K +$547K +13,516 New
Nomura Holdings
168
Nomura Holdings
Japan
$545K +$545K +13,501 New
Nomura Asset Management
169
Nomura Asset Management
Japan
$544K +$48.6K +1,200 +10%
Canada Pension Plan Investment Board
170
Canada Pension Plan Investment Board
Ontario, Canada
$543K +$203K +5,004 +60%
PNC Financial Services Group
171
PNC Financial Services Group
Pennsylvania
$526K -$594K -14,695 -53%
Comerica Bank
172
Comerica Bank
Texas
$518K +$11.3K +267 +2%
Janus Henderson Group
173
Janus Henderson Group
United Kingdom
$517K – – –
Squarepoint
174
Squarepoint
New York
$514K +$125K +3,100 +32%
LTFS
175
Ladenburg Thalmann Financial Services
Florida
$508K +$84.7K +2,091 +20%
5 6
7
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