Comerica Bank
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Comerica Bank’s Ionis Pharmaceuticals IONS Stock Holding History

Comerica Bank’s Portfolio IONS Stock Details IONS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		$316K Buy
3,997
+1,810
+83% +$136K ﹤0.01% 2081
2025
Q3 		$143K Buy
2,187
+570
+35% +$27.8K ﹤0.01% 2476
2025
Q2 		$63.9K Buy
1,617
+297
+23% +$9.72K ﹤0.01% 2730
2025
Q1 		$39.8K Sell
1,320
-6,073
-82% -$199K ﹤0.01% 2853
2024
Q4 		$258K Sell
7,393
-222
-3% -$8.3K ﹤0.01% 2200
2024
Q3 		$305K Sell
7,615
-13,809
-64% -$642K ﹤0.01% 2119
2024
Q2 		$1.02M Sell
21,424
-18,067
-46% -$741K ﹤0.01% 1477
2024
Q1 		$1.71M Sell
39,491
-123
-0.3% -$5.86K 0.01% 1257
2023
Q4 		$2M Sell
39,614
-334
-0.8% -$16K 0.01% 1156
2023
Q3 		$1.81M Buy
39,948
+39,410
+7,325% +$1.63M 0.01% 1133
2023
Q2 		$6 Buy
+538
New +$20.7K ﹤0.01% 436
2022
Q4 		$459K Sell
11,522
-17
-0.1% -$715 ﹤0.01% 1812
2022
Q3 		$516K Sell
11,539
-145
-1% -$6.11K ﹤0.01% 1772
2022
Q2 		$459K Sell
11,684
-71
-0.6% -$2.68K ﹤0.01% 1866
2022
Q1 		$506K Hold
11,755
– – ﹤0.01% 1863
2021
Q4 		$370K Sell
11,755
-75
-0.6% -$2.36K ﹤0.01% 1963
2021
Q3 		$360K Sell
11,830
-3,761
-24% -$142K ﹤0.01% 2021
2021
Q2 		$590K Sell
15,591
-105
-0.7% -$4.11K ﹤0.01% 1962
2021
Q1 		$670K Sell
15,696
-352
-2% -$19.6K ﹤0.01% 1928
2020
Q4 		$991K Sell
16,048
-466
-3% -$23.2K 0.01% 1724
2020
Q3 		$782K Sell
16,514
-62
-0.4% -$3.44K 0.01% 1701
2020
Q2 		$1.01M Buy
16,576
+297
+2% +$16.5K 0.01% 1505
2020
Q1 		$946K Buy
16,279
+400
+3% +$22.3K 0.01% 1384
2019
Q4 		$946K Buy
15,879
+205
+1% +$12.2K 0.01% 1586
2019
Q3 		$844K Buy
15,674
+84
+0.5% +$5.47K 0.01% 1617
2019
Q2 		$1.05M Buy
15,590
+170
+1% +$12K 0.01% 1504
2019
Q1 		$1.32M Sell
15,420
-4
-0% -$258 0.01% 1405
2018
Q4 		$842K Sell
15,424
-368
-2% -$18.8K 0.01% 1650
2018
Q3 		$771K Sell
15,792
-164
-1% -$7.71K 0.01% 1711
2018
Q2 		$704K Buy
15,956
+8
+0.1% +$355 ﹤0.01% 1811
2018
Q1 		$731K Sell
15,948
-121
-0.8% -$6.15K 0.01% 1765
2017
Q4 		$857K Sell
16,069
-112
-0.7% -$6.14K 0.01% 1721
2017
Q3 		$944K Buy
16,181
+10
+0.1% +$524 0.01% 1638
2017
Q2 		$963K Sell
16,171
-373
-2% -$17.4K 0.01% 1604
2017
Q1 		$787K Buy
16,544
+39
+0.2% +$1.75K 0.01% 1708
2016
Q4 		$794K Buy
16,505
+4,122
+33% +$163K 0.01% 1690
2016
Q3 		$424K Buy
12,383
+355
+3% +$11.1K ﹤0.01% 1833
2016
Q2 		$437K Sell
12,028
-165
-1% -$5.32K ﹤0.01% 1828
2016
Q1 		$518K Buy
12,193
+267
+2% +$10.8K ﹤0.01% 1747
2015
Q4 		$678K Sell
11,926
-490
-4% -$26.4K 0.01% 1594
2015
Q3 		$502K Sell
12,416
-11,996
-49% -$621K ﹤0.01% 1712
2015
Q2 		$1.4M Buy
24,412
+12,187
+100% +$775K 0.01% 1643
2015
Q1 		$778K Sell
12,225
-12,411
-50% -$842K 0.01% 1602
2014
Q4 		$1.52M Buy
24,636
+12,447
+102% +$614K 0.01% 1592
2014
Q3 		$473K Sell
12,189
-1,017
-8% -$36K ﹤0.01% 1788
2014
Q2 		$455K Sell
13,206
-9,010
-41% -$284K ﹤0.01% 1829
2014
Q1 		$960K Buy
22,216
+413
+2% +$20K 0.01% 1579
2013
Q4 		$868K Sell
21,803
-31,696
-59% -$1.13M 0.01% 1627
2013
Q3 		$2.01M Sell
53,499
-5,042
-9% -$151K 0.01% 1135
2013
Q2 		$1.57M Buy
+58,541
New +$1.24M 0.01% 1103

Other funds holding IONS

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Capital World Investors
Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
BG
Bellevue Group Kuesnacht, Switzerland $4.2B AUM 54.85% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Two Sigma Advisers
Two Sigma Advisers New York $51.4B AUM 31.07% 1-Year Est. Return

Comerica Bank's IONS Position: Q4 2025 in Review

Comerica Bank increased its Ionis Pharmaceuticals (IONS) stake by 83% in Q4 2025, buying an estimated $136K and bringing the position to 3,997 shares worth $316K. The position accounts for ﹤0.01% of the portfolio, ranked #2081.

Comerica Bank first reported a position in IONS in Q2 2013 and has held it in 50 quarters since. The position peaked at $2.01M in Q3 2013. 492 funds tracked by Wall St. Rank hold IONS as of Q4 2025.

  • Comerica Bank held 3,997 shares of Ionis Pharmaceuticals worth $316K as of Q4 2025.
  • Comerica Bank bought 1,810 Ionis Pharmaceuticals shares in Q4 2025, an estimated $136K.
  • Ionis Pharmaceuticals made up ﹤0.01% of Comerica Bank's portfolio in Q4 2025, its #2081 holding.
  • Comerica Bank first reported a position in Ionis Pharmaceuticals in Q2 2013 and has held it in 50 quarters since.
  • Comerica Bank's Ionis Pharmaceuticals position peaked at $2.01M in Q3 2013.
  • 492 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q4 2025.

Based on Comerica Bank's 13F filing for Q4 2025, filed 29 Jan 2026.