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Ionis Pharmaceuticals

493 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 74 funds opening new positions, 177 increasing their positions, 156 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more first-time investments, than exits

New positions opened: 74 | Existing positions closed: 65

13% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 156

8% more funds holding in top 10

Funds holding in top 10: 1314 (+1)

0% more funds holding

Funds holding: 491493 (+2)

0.72% less ownership

Funds ownership: 105.2%104.48% (-0.72%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$512M)

Holders
493
Holders Change
+2
Holders Change %
+0.41%
% of All Funds
6.07%
Holding in Top 10
14
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.69%
% of All Funds
0.17%
New
74
Increased
177
Reduced
156
Closed
65
Calls
$141M
Puts
$144M
Net Calls
-$2.9M
Net Calls Change
-$54M
Name Holding Trade Value Shares
Change
Change in
Stake
EF
126
Empowered Funds
Pennsylvania
$7.74M +$8.14M +103,141 New
GAM
127
Gotham Asset Management
New York
$7.43M +$4.4M +55,756 +129%
State of Wisconsin Investment Board
128
State of Wisconsin Investment Board
Wisconsin
$7.25M +$137K +1,730 +2%
SPS
129
Susquehanna Portfolio Strategies
Pennsylvania
$7.21M
Marshall Wace
130
Marshall Wace
United Kingdom
$7.21M -$12.7M -160,979 -63%
EI
131
EFG International
$7.06M +$1.48M +18,704 +25%
Envestnet Asset Management
132
Envestnet Asset Management
Illinois
$7.01M +$273K +3,463 +4%
RPAM
133
Rhenman & Partners Asset Management
Sweden
$6.98M -$5.18M -65,600 -41%
DekaBank Deutsche Girozentrale
134
DekaBank Deutsche Girozentrale
Germany
$6.92M
Sumitomo Mitsui Trust Group
135
Sumitomo Mitsui Trust Group
Japan
$6.15M -$937K -11,875 -13%
NAMA
136
Nikko Asset Management Americas
New York
$6.13M -$937K -11,875 -13%
XT
137
XTX Topco
Cayman Islands
$6.05M +$5.02M +63,602 +376%
CL
138
CSS LLC
Illinois
$5.94M +$6.24M +79,093 New
CUAMC
139
China Universal Asset Management Company
China
$5.81M +$2.76M +34,921 +82%
BFM
140
Boothbay Fund Management
New York
$5.75M +$79.6K +1,009 +1%
LCG
141
Lisanti Capital Growth
New York
$5.68M +$3.39M +42,910 +131%
VGA
142
Vanguard Global Advisers
Pennsylvania
$5.4M +$5.68M +71,911 New
HIM
143
Hillsdale Investment Management
Ontario, Canada
$5.32M
EAM
144
Erste Asset Management
Austria
$5.21M
VOYA Investment Management
145
VOYA Investment Management
Georgia
$5.19M -$365K -4,624 -6%
EP
146
Edgestream Partners
New Jersey
$5.13M +$5.4M +68,369 New
Janus Henderson Group
147
Janus Henderson Group
United Kingdom
$5.12M
Treasurer of the State of North Carolina
148
Treasurer of the State of North Carolina
North Carolina
$5.08M +$114K +1,439 +2%
PFSRSONJ
149
Police & Firemen's Retirement System of New Jersey
New Jersey
$5.06M +$37.4K +474 +0.7%
Walleye Capital
150
Walleye Capital
New York
$4.95M +$5.18M +65,624 +20,192%