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Ionis Pharmaceuticals

493 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 74 funds opening new positions, 177 increasing their positions, 156 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more first-time investments, than exits

New positions opened: 74 | Existing positions closed: 65

13% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 156

8% more funds holding in top 10

Funds holding in top 10: 1314 (+1)

0% more funds holding

Funds holding: 491493 (+2)

0.72% less ownership

Funds ownership: 105.2%104.48% (-0.72%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$512M)

Holders
493
Holders Change
+2
Holders Change %
+0.41%
% of All Funds
6.07%
Holding in Top 10
14
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.69%
% of All Funds
0.17%
New
74
Increased
177
Reduced
156
Closed
65
Calls
$141M
Puts
$144M
Net Calls
-$2.9M
Net Calls Change
-$54M
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of New York Mellon
51
Bank of New York Mellon
New York
$38.6M -$1.84M -23,269 -4%
PA
52
Perceptive Advisors
New York
$37.8M +$39.8M +504,000 New
BCM
53
Boone Capital Management
Georgia
$37.6M +$6.53M +82,689 +20%
CS
54
Candriam SCA
Luxembourg
$36.3M -$15.3M -193,576 -29%
BNP Paribas Financial Markets
55
BNP Paribas Financial Markets
France
$36M +$11.4M +144,852 +43%
Alyeska Investment Group
56
Alyeska Investment Group
Illinois
$35.5M -$676K -8,561 -2%
First Trust Advisors
57
First Trust Advisors
Illinois
$35.2M -$4.49M -56,876 -11%
Neuberger Berman Group
58
Neuberger Berman Group
New York
$33.3M +$26.5M +335,228 +310%
PA
59
Pinnacle Associates
New York
$32.8M -$2.01M -25,511 -6%
D.E. Shaw & Co
60
D.E. Shaw & Co
New York
$32.3M +$7.64M +96,796 +29%
AllianceBernstein
61
AllianceBernstein
Tennessee
$31.7M +$4.64M +58,820 +17%
DCP
62
Davern Capital Partners
New York
$29.1M +$11.7M +148,426 +62%
CWG
63
C WorldWide Group
Denmark
$27.5M
New York State Common Retirement Fund
64
New York State Common Retirement Fund
New York
$26.3M +$8.57M +108,561 +45%
Capital Research Global Investors
65
Capital Research Global Investors
California
$24.3M +$25.5M +323,015 New
Renaissance Technologies
66
Renaissance Technologies
New York
$22.9M +$6.47M +81,942 +37%
Swiss National Bank
67
Swiss National Bank
Switzerland
$22.9M +$474K +6,000 +2%
Hudson Bay Capital Management
68
Hudson Bay Capital Management
Connecticut
$22.2M -$14.2M -179,900 -38%
Legal & General Group
69
Legal & General Group
United Kingdom
$22.1M -$2.4M -30,469 -9%
PFM
70
Privium Fund Management
Netherlands
$21.8M +$3.88M +49,200 +20%
Barclays
71
Barclays
United Kingdom
$21.8M -$43.6M -552,997 -66%
AIM
72
ARK Investment Management
Florida
$21.7M -$10.6M -134,252 -32%
TCM
73
TimesSquare Capital Management
New York
$20.7M +$21.8M +275,674 New
Dimensional Fund Advisors
74
Dimensional Fund Advisors
Texas
$20.1M +$7.2M +91,180 +52%
California Public Employees Retirement System
75
California Public Employees Retirement System
California
$19.2M +$3.32M +42,117 +20%