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Ionis Pharmaceuticals

338 hedge funds and large institutions have $4.92B invested in Ionis Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 50 funds opening new positions, 115 increasing their positions, 107 reducing their positions, and 54 closing their positions.

New
Increased
Maintained
Reduced
Closed

19% more call options, than puts

Call options by funds: $15.2M | Put options by funds: $12.8M

2.93% more ownership

Funds ownership: 89.04%91.97% (+2.9%)

7% more repeat investments, than reductions

Existing positions increased: 115 | Existing positions reduced: 107

7% less first-time investments, than exits

New positions opened: 50 | Existing positions closed: 54

3% less funds holding

Funds holding: 349338 (-11)

11% less capital invested

Capital invested by funds: $5.53B → $4.92B (-$618M)

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

Holders
338
Holders Change
-11
Holders Change %
-3.15%
% of All Funds
5.43%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.06%
New
50
Increased
115
Reduced
107
Closed
54
Calls
$15.2M
Puts
$12.8M
Net Calls
+$2.46M
Net Calls Change
-$7.76M
Name Holding Trade Value Shares
Change
Change in
Stake
Swiss National Bank
51
Swiss National Bank
Switzerland
$11.6M +$244K +5,800 +2%
ECM
52
ExodusPoint Capital Management
New York
$11.5M +$12.5M +297,973 +4,643%
Corient Private Wealth
53
Corient Private Wealth
Florida
$11.4M +$12.7M +302,677 New
D.E. Shaw & Co
54
D.E. Shaw & Co
New York
$11.3M +$3.78M +89,786 +43%
Stifel Financial
55
Stifel Financial
Missouri
$10.2M -$1.27M -30,269 -10%
RG
56
Redmile Group
California
$10.1M -$5.95M -141,472 -35%
SSA
57
Schonfeld Strategic Advisors
New York
$10M +$2.44M +58,126 +28%
SA
58
Sicart Associates
New York
$9.3M -$325K -7,718 -3%
Bank of Montreal
59
Bank of Montreal
Ontario, Canada
$9.21M -$4.27M -101,551 -31%
EP
60
Eversept Partners
New York
$9.1M +$1.65M +39,142 +19%
Connor, Clark & Lunn Investment Management (CC&L)
61
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$8.71M +$63.8K +1,516 +0.7%
Man Group
62
Man Group
United Kingdom
$8.71M +$2.23M +52,928 +30%
RJA
63
Raymond James & Associates
Florida
$8.52M -$534K -12,698 -5%
Hudson Bay Capital Management
64
Hudson Bay Capital Management
Connecticut
$8.5M +$1.06M +25,200 +13%
Rafferty Asset Management
65
Rafferty Asset Management
New York
$8.27M +$2.82M +67,005 +44%
Two Sigma Investments
66
Two Sigma Investments
New York
$7.6M -$3.86M -91,727 -31%
TCM
67
Tang Capital Management
California
$7.55M
JFG
68
Jefferies Financial Group
New York
$7.44M +$8.29M +197,009 New
BNP Paribas Financial Markets
69
BNP Paribas Financial Markets
France
$7.25M +$2.49M +59,207 +45%
FAM
70
Fred Alger Management
New York
$7.19M +$2.01M +47,831 +34%
Russell Investments Group
71
Russell Investments Group
United Kingdom
$7.19M +$4.12M +97,978 +106%
CS
72
Credit Suisse
Switzerland
$6.96M +$1.25M +29,604 +19%
Squarepoint
73
Squarepoint
New York
$6.84M +$3.74M +88,953 +97%
UBS AM
74
UBS AM
Illinois
$6.64M -$4.37M -103,828 -37%
California State Teachers Retirement System (CalSTRS)
75
California State Teachers Retirement System (CalSTRS)
California
$6.34M +$82K +1,950 +1%

IONS Hedge Fund Activity: Q4 2022 in Review

338 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2022, worth a combined $4.92B — down 11% from $5.53B a quarter earlier.

Sellers outnumbered buyers: 54 funds closed out of IONS and 50 opened new positions — a net loss of 4 holders — while 107 trimmed existing stakes and 115 added.

The largest buyer was OrbiMed, adding an estimated $51.5M. The largest seller was BVF Inc, cutting an estimated $73.7M.

  • 338 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2022, down from 349 in Q3 2022.
  • Funds reported $4.92B of Ionis Pharmaceuticals stock for Q4 2022, down 11% quarter-over-quarter.
  • 50 funds opened new Ionis Pharmaceuticals positions in Q4 2022 and 54 closed out, a net change of -4 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2022 was OrbiMed, an estimated $51.5M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2022 was BVF Inc, an estimated $73.7M sold.

Based on aggregated 13F filings for Q4 2022.