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Ionis Pharmaceuticals

340 hedge funds and large institutions have $3.75B invested in Ionis Pharmaceuticals in 2021 Q4 according to their latest regulatory filings, with 59 funds opening new positions, 106 increasing their positions, 119 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

55% more first-time investments, than exits

New positions opened: 59 | Existing positions closed: 38

5% more funds holding

Funds holding: 324340 (+16)

1.03% more ownership

Funds ownership: 86.24%87.27% (+1%)

8% less capital invested

Capital invested by funds: $4.08B → $3.75B (-$332M)

11% less repeat investments, than reductions

Existing positions increased: 106 | Existing positions reduced: 119

43% less call options, than puts

Call options by funds: $14.9M | Put options by funds: $26.4M

Holders
340
Holders Change
+16
Holders Change %
+4.94%
% of All Funds
5.23%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
59
Increased
106
Reduced
119
Closed
38
Calls
$14.9M
Puts
$26.4M
Net Calls
-$11.5M
Net Calls Change
-$18M
Name Holding Trade Value Shares
Change
Change in
Stake
CSS
51
Cubist Systematic Strategies
Connecticut
$9.04M +$6.62M +210,428 +243%
California Public Employees Retirement System
52
California Public Employees Retirement System
California
$8.65M -$117K -3,704 -1%
SA
53
Sicart Associates
New York
$8.63M -$275K -8,723 -3%
Swiss National Bank
54
Swiss National Bank
Switzerland
$8.5M -$18.9K -600 -0.2%
Voloridge Investment Management
55
Voloridge Investment Management
Florida
$8.12M +$8.4M +266,845 New
RJA
56
Raymond James & Associates
Florida
$7.85M -$1.37M -43,464 -14%
Bank of Montreal
57
Bank of Montreal
Ontario, Canada
$7.17M -$639K -20,297 -8%
Renaissance Technologies
58
Renaissance Technologies
New York
$7.02M +$4.19M +133,100 +136%
PPA
59
Parametric Portfolio Associates
Washington
$6.85M -$201K -6,400 -3%
MIS
60
Morningstar Investment Services
Illinois
$6.68M +$167K +5,291 +2%
SGA
61
Sector Gamma AS
Norway
$6.38M -$1.71M -54,333 -21%
Susquehanna International Group
62
Susquehanna International Group
Pennsylvania
$6.21M +$947K +30,089 +17%
MSE
63
MUFG Securities EMEA
United Kingdom
$6.09M +$6.3M +200,000 New
Russell Investments Group
64
Russell Investments Group
United Kingdom
$5.91M -$1.19M -37,720 -16%
UBS Group
65
UBS Group
Switzerland
$5.89M +$1.91M +60,777 +46%
Balyasny Asset Management
66
Balyasny Asset Management
Illinois
$5.88M +$1.61M +51,105 +36%
Rafferty Asset Management
67
Rafferty Asset Management
New York
$5.77M +$2.92M +92,902 +96%
Citigroup
68
Citigroup
New York
$5.66M +$2.05M +64,983 +54%
California State Teachers Retirement System (CalSTRS)
69
California State Teachers Retirement System (CalSTRS)
California
$5.6M -$1.32M -41,987 -19%
UBS AM
70
UBS AM
Illinois
$5.59M +$97.2K +3,087 +2%
PAMS
71
Pictet Asset Management (Switzerland)
Switzerland
$5.57M +$1.49M +47,391 +35%
Tudor Investment Corp
72
Tudor Investment Corp
Connecticut
$5.43M -$731K -23,227 -12%
CS
73
Credit Suisse
Switzerland
$5.38M -$186K -5,895 -3%
MAM
74
Majedie Asset Management
United Kingdom
$5.35M
TCM
75
Tekla Capital Management
Massachusetts
$5.35M -$4.62M -146,841 -46%

IONS Hedge Fund Activity: Q4 2021 in Review

340 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2021, worth a combined $3.75B — down 8.1% from $4.08B a quarter earlier.

Buyers outnumbered sellers: 59 funds opened new IONS positions and 38 closed out — a net gain of 21 holders — while 106 added to existing stakes and 119 trimmed.

The largest buyer was Millennium Management, adding an estimated $42.2M. The largest seller was ClearBridge Investments, cutting an estimated $45.5M.

  • 340 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2021, up from 324 in Q3 2021.
  • Funds reported $3.75B of Ionis Pharmaceuticals stock for Q4 2021, down 8.1% quarter-over-quarter.
  • 59 funds opened new Ionis Pharmaceuticals positions in Q4 2021 and 38 closed out, a net change of +21 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2021 was Millennium Management, an estimated $42.2M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2021 was ClearBridge Investments, an estimated $45.5M sold.

Based on aggregated 13F filings for Q4 2021.