Cubist Systematic Strategies’s Ionis Pharmaceuticals IONS Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2025
Q3
$3.18M Buy
+48,654
New +$2.38M 0.02% 1271
2024
Q3
Sell
-35,311
Closed -$1.68M 3230
2024
Q2
$1.68M Sell
35,311
-242,480
-87% -$9.95M 0.01% 1443
2024
Q1
$12M Buy
277,791
+78,314
+39% +$3.73M 0.07% 401
2023
Q4
$10.1M Buy
+199,477
New +$9.55M 0.07% 445
2023
Q3
Sell
-84,961
Closed -$3.49M 3630
2023
Q2
$3.49M Buy
+84,961
New +$3.26M 0.02% 1068
2023
Q1
Sell
-128,070
Closed -$4.84M 4145
2022
Q4
$4.84M Buy
128,070
+57,662
+82% +$2.43M 0.03% 1041
2022
Q3
$3.11M Sell
70,408
-78,980
-53% -$3.33M 0.02% 1556
2022
Q2
$5.53M Buy
149,388
+53,858
+56% +$2.03M 0.03% 897
2022
Q1
$3.54M Sell
95,530
-201,652
-68% -$6.6M 0.03% 1011
2021
Q4
$9.04M Buy
297,182
+210,428
+243% +$6.62M 0.09% 293
2021
Q3
$2.91M Sell
86,754
-91,388
-51% -$3.44M 0.04% 776
2021
Q2
$7.11M Buy
+178,142
New +$6.98M 0.08% 353
2021
Q1
Sell
-78,852
Closed -$4.46M 2895
2020
Q4
$4.46M Buy
78,852
+16,670
+27% +$831K 0.06% 499
2020
Q3
$2.95M Buy
62,182
+57,882
+1,346% +$3.22M 0.04% 674
2020
Q2
$254K Sell
4,300
-33,607
-89% -$1.87M ﹤0.01% 1922
2020
Q1
$1.79M Buy
37,907
+3,593
+10% +$200K 0.05% 518
2019
Q4
$2.07M Buy
34,314
+28,502
+490% +$1.7M 0.04% 728
2019
Q3
$348K Sell
5,812
-39,872
-87% -$2.6M 0.01% 1477
2019
Q2
$2.94M Sell
45,684
-12,719
-22% -$899K 0.05% 506
2019
Q1
$4.74M Buy
+58,403
New +$3.77M 0.15% 145
2018
Q4
Sell
-924
Closed -$48K 2168
2018
Q3
$48K Buy
+924
New +$43.4K ﹤0.01% 1712
2018
Q2
Sell
-20,015
Closed -$882K 1907
2018
Q1
$882K Sell
20,015
-6,002
-23% -$305K 0.05% 489
2017
Q4
$1.31M Buy
26,017
+19,427
+295% +$1.07M 0.07% 366
2017
Q3
$334K Sell
6,590
-6,674
-50% -$350K 0.02% 1084
2017
Q2
$675K Buy
+13,264
New +$618K 0.04% 608
2017
Q1
Sell
-36,134
Closed -$1.73M 1728
2016
Q4
$1.73M Buy
+36,134
New +$1.43M 0.14% 187
2016
Q3
Sell
-37,083
Closed -$864K 1766
2016
Q2
$864K Buy
37,083
+25,587
+223% +$825K 0.05% 509
2016
Q1
$466K Buy
11,496
+10,365
+916% +$421K 0.03% 789
2015
Q4
$70K Sell
1,131
-58,374
-98% -$3.15M ﹤0.01% 1561
2015
Q3
$2.4M Sell
59,505
-18,230
-23% -$944K 0.12% 191
2015
Q2
$4.47M Buy
77,735
+48,637
+167% +$3.09M 0.22% 84
2015
Q1
$1.85M Buy
+29,098
New +$1.97M 0.09% 303
2014
Q4
Sell
-79,594
Closed -$3.09M 1967
2014
Q3
$3.09M Buy
79,594
+10,799
+16% +$383K 0.19% 123
2014
Q2
$2.37M Buy
+68,795
New +$2.17M 0.14% 186

Other funds holding IONS

Cubist Systematic Strategies's IONS Position: Q3 2025 in Review

Cubist Systematic Strategies opened a new position in Ionis Pharmaceuticals (IONS) in Q3 2025: 48,654 shares worth $3.18M. The stake represents 0.02% of the portfolio and ranks #1271 among its holdings. This is a return to the name: Cubist Systematic Strategies previously reported a position in IONS as recently as Q2 2024.

Cubist Systematic Strategies first reported a position in IONS in Q2 2014 and has held it in 34 quarters since. The position peaked at $12M in Q1 2024. 435 funds tracked by Wall St. Rank hold IONS as of Q3 2025.

  • Cubist Systematic Strategies held 48,654 shares of Ionis Pharmaceuticals worth $3.18M as of Q3 2025.
  • Ionis Pharmaceuticals was a new Cubist Systematic Strategies position in Q3 2025.
  • Ionis Pharmaceuticals made up 0.02% of Cubist Systematic Strategies's portfolio in Q3 2025, its #1271 holding.
  • Cubist Systematic Strategies first reported a position in Ionis Pharmaceuticals in Q2 2014 and has held it in 34 quarters since.
  • Cubist Systematic Strategies's Ionis Pharmaceuticals position peaked at $12M in Q1 2024.
  • 435 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q3 2025.

Based on Cubist Systematic Strategies's 13F filing for Q3 2025, filed 14 Nov 2025.