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Ionis Pharmaceuticals

332 hedge funds and large institutions have $4.62B invested in Ionis Pharmaceuticals in 2022 Q1 according to their latest regulatory filings, with 47 funds opening new positions, 107 increasing their positions, 109 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 24 (+2)

23% more capital invested

Capital invested by funds: $3.75B → $4.62B (+$875M)

0.94% more ownership

Funds ownership: 87.27%88.21% (+0.94%)

2% less repeat investments, than reductions

Existing positions increased: 107 | Existing positions reduced: 109

6% less first-time investments, than exits

New positions opened: 47 | Existing positions closed: 50

2% less funds holding

Funds holding: 340332 (-8)

44% less call options, than puts

Call options by funds: $11.4M | Put options by funds: $20.2M

Holders
332
Holders Change
-8
Holders Change %
-2.35%
% of All Funds
5.24%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.06%
New
47
Increased
107
Reduced
109
Closed
50
Calls
$11.4M
Puts
$20.2M
Net Calls
-$8.8M
Net Calls Change
+$2.67M
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Advisers
26
Two Sigma Advisers
New York
$22.7M +$3.74M +114,200 +23%
Sumitomo Mitsui Trust Group
27
Sumitomo Mitsui Trust Group
Japan
$22.2M -$206K -6,286 -1%
NAMA
28
Nikko Asset Management Americas
New York
$21.5M -$206K -6,286 -1%
Bank of New York Mellon
29
Bank of New York Mellon
New York
$20.3M -$240K -7,330 -1%
PA
30
Pinnacle Associates
New York
$19.3M -$624K -19,076 -4%
Morgan Stanley
31
Morgan Stanley
New York
$19.2M +$1.79M +54,592 +12%
CS
32
Candriam SCA
Luxembourg
$18.5M -$14.3M -437,088 -47%
Royal Bank of Canada
33
Royal Bank of Canada
Ontario, Canada
$16.5M -$1.18M -36,146 -8%
Nomura Holdings
34
Nomura Holdings
Japan
$15.3M +$709K +21,674 +6%
Assenagon Asset Management
35
Assenagon Asset Management
Luxembourg
$13.3M +$10.1M +309,495 +639%
Dimensional Fund Advisors
36
Dimensional Fund Advisors
Texas
$13.1M -$1.09M -33,210 -9%
Baillie Gifford & Co
37
Baillie Gifford & Co
United Kingdom
$12.9M +$1.08M +33,043 +10%
Stifel Financial
38
Stifel Financial
Missouri
$12.6M -$569K -17,382 -5%
Barclays
39
Barclays
United Kingdom
$11.7M -$445K -13,588 -4%
SA
40
Sicart Associates
New York
$11.3M +$728K +22,251 +8%
DY
41
Dowling & Yahnke
California
$11.2M +$4.91K +150 +0%
Swiss National Bank
42
Swiss National Bank
Switzerland
$11.1M +$694K +21,200 +8%
N
43
Nuveen
North Carolina
$11M -$1.17M -35,657 -10%
California Public Employees Retirement System
44
California Public Employees Retirement System
California
$10.9M +$340K +10,391 +4%
Russell Investments Group
45
Russell Investments Group
United Kingdom
$10.5M +$2.95M +89,985 +46%
Bank of Montreal
46
Bank of Montreal
Ontario, Canada
$9.58M +$1.28M +39,090 +17%
RJA
47
Raymond James & Associates
Florida
$9.51M -$41.2K -1,259 -0.5%
PPA
48
Parametric Portfolio Associates
Washington
$8.55M +$187K +5,698 +3%
MIS
49
Morningstar Investment Services
Illinois
$8M +$106K +3,249 +1%
Hudson Bay Capital Management
50
Hudson Bay Capital Management
Connecticut
$7.78M -$3.11M -95,000 -31%

IONS Hedge Fund Activity: Q1 2022 in Review

332 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q1 2022, worth a combined $4.62B — up 23% from $3.75B a quarter earlier.

Sellers outnumbered buyers: 50 funds closed out of IONS and 47 opened new positions — a net loss of 3 holders — while 109 trimmed existing stakes and 107 added.

The largest buyer was Tweedy, Browne Co, opening a new position worth an estimated $95.7M. The largest seller was Millennium Management, cutting an estimated $46.9M.

  • 332 institutional investors held Ionis Pharmaceuticals (IONS) as of Q1 2022, down from 340 in Q4 2021.
  • Funds reported $4.62B of Ionis Pharmaceuticals stock for Q1 2022, up 23% quarter-over-quarter.
  • 47 funds opened new Ionis Pharmaceuticals positions in Q1 2022 and 50 closed out, a net change of -3 holders.
  • The largest Ionis Pharmaceuticals buyer in Q1 2022 was Tweedy, Browne Co, an estimated $95.7M added.
  • The largest Ionis Pharmaceuticals seller in Q1 2022 was Millennium Management, an estimated $46.9M sold.

Based on aggregated 13F filings for Q1 2022.