|
1
|
Avoro Capital Advisors
New York
|
–
|
-$2.23B
|
-26,250,000
|
Closed
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-$1.54B
|
-18,109,323
|
Closed
|
|
|
3
|
|
–
|
-$1.14B
|
-13,385,970
|
Closed
|
|
|
4
|
HBK Investments
Dallas,
Texas
|
–
|
-$553M
|
-6,500,000
|
Closed
|
|
|
5
|
Farallon Capital Management
San Francisco,
California
|
–
|
-$498M
|
-5,860,000
|
Closed
|
|
|
6
|
|
–
|
-$418M
|
-4,916,448
|
Closed
|
|
|
7
|
Palo Alto Investors
Palo Alto,
California
|
–
|
-$413M
|
-4,852,383
|
Closed
|
|
|
8
|
Boxer Capital
San Diego,
California
|
–
|
-$383M
|
-4,500,000
|
Closed
|
|
|
9
|
|
–
|
-$372M
|
-4,373,178
|
Closed
|
|
|
10
|
Pentwater Capital Management
Naples,
Florida
|
–
|
-$333M
|
-3,920,000
|
Closed
|
|
|
11
|
State Street
Boston,
Massachusetts
|
–
|
-$310M
|
-3,648,078
|
Closed
|
|
|
12
|
Redmile Group
San Francisco,
California
|
–
|
-$275M
|
-3,234,934
|
Closed
|
|
|
13
|
Davidson Kempner Capital Management
New York
|
–
|
-$258M
|
-3,041,691
|
Closed
|
|
|
14
|
Millennium Management
New York
|
–
|
-$234M
|
-2,750,749
|
Closed
|
|
|
15
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
–
|
-$216M
|
-2,542,082
|
Closed
|
|
|
16
|
Citadel Advisors
Miami,
Florida
|
–
|
-$213M
|
-2,506,602
|
Closed
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-$200M
|
-2,352,580
|
Closed
|
|
|
18
|
|
–
|
-$197M
|
-2,316,348
|
Closed
|
|
|
19
|
Deerfield Management
New York
|
–
|
-$196M
|
-2,304,900
|
Closed
|
|
|
20
|
Jennison Associates
New York
|
–
|
-$181M
|
-2,127,474
|
Closed
|
|
|
21
|
Fidelity Investments
Boston,
Massachusetts
|
–
|
-$168M
|
-1,974,455
|
Closed
|
|
|
22
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
–
|
-$164M
|
-1,927,230
|
Closed
|
|
|
23
|
TIG Advisors LLC
New York
|
–
|
-$162M
|
-1,899,813
|
Closed
|
|
|
24
|
Franklin Resources
San Mateo,
California
|
–
|
-$150M
|
-1,769,944
|
Closed
|
|
|
25
|
Ameriprise
Minneapolis,
Minnesota
|
–
|
-$149M
|
-1,748,127
|
Closed
|
|
