|
1
|
Avoro Capital Advisors
New York
|
$247M
|
+$14.3M
|
+875,000
|
+5%
|
|
|
2
|
|
$132M
|
-$498K
|
-30,497
|
-0.3%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$125M
|
+$52M
|
+3,183,505
|
+59%
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$114M
|
+$49.2M
|
+3,014,073
|
+63%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$102M
|
+$5.75M
|
+351,799
|
+5%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$92.4M
|
-$1.21M
|
-74,045
|
-1%
|
|
|
7
|
Acuta Capital Partners
Redwood City,
California
|
$85.5M
|
-$14.7M
|
-900,000
|
-13%
|
|
|
8
|
|
$83.4M
|
-$44.9M
|
-2,750,953
|
-33%
|
|
|
9
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$72.3M
|
-$4.52M
|
-276,739
|
-5%
|
|
|
10
|
Palo Alto Investors
Palo Alto,
California
|
$70.1M
|
+$355K
|
+21,747
|
+0.5%
|
|
|
11
|
Millennium Management
New York
|
$40.7M
|
-$57.1M
|
-3,495,808
|
-56%
|
|
|
12
|
NEA Management Company
Timonium,
Maryland
|
$40.5M
|
–
|
–
|
–
|
|
|
13
|
Foresite Capital Management III
Larkspur,
California
|
$39.4M
|
–
|
–
|
–
|
|
|
14
|
Jennison Associates
New York
|
$30.8M
|
+$4.57M
|
+279,463
|
+15%
|
|
|
15
|
Janus Henderson Group
London,
|
$28.2M
|
+$6.78M
|
+415,121
|
+27%
|
|
|
16
|
Victory Capital Management
San Antonio,
Texas
|
$27.4M
|
+$12.5M
|
+762,648
|
+69%
|
|
|
17
|
Ghost Tree Capital
New York
|
$27M
|
+$5.1M
|
+312,000
|
+20%
|
|
|
18
|
Citadel Advisors
Miami,
Florida
|
$26.6M
|
-$42.7M
|
-2,611,787
|
-59%
|
|
|
19
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$23.4M
|
-$310K
|
-18,965
|
-1%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$18.4M
|
+$121K
|
+7,396
|
+0.6%
|
|
|
21
|
Ameriprise
Minneapolis,
Minnesota
|
$17.9M
|
+$10.2M
|
+627,077
|
+104%
|
|
|
22
|
Nexthera Capital
New York
|
$15.8M
|
+$11.1M
|
+676,882
|
+167%
|
|
|
23
|
Foresite Capital Management IV
Larkspur,
California
|
$15.7M
|
–
|
–
|
–
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$15.3M
|
+$808K
|
+49,434
|
+5%
|
|
|
25
|
First Light Asset Management
Edina,
Minnesota
|
$14.9M
|
+$1.23M
|
+75,516
|
+8%
|
|
