|
1
|
Avoro Capital Advisors
New York
|
$419M
|
+$15.6M
|
+775,000
|
+5%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$335M
|
+$113M
|
+5,605,289
|
+65%
|
|
|
3
|
|
$266M
|
+$44.1M
|
+2,195,066
|
+24%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$208M
|
+$36M
|
+1,790,358
|
+26%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$201M
|
+$14.1M
|
+699,658
|
+9%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$126M
|
-$20M
|
-996,270
|
-16%
|
|
|
7
|
|
$117M
|
-$15.4M
|
-766,201
|
-13%
|
|
|
8
|
Palo Alto Investors
Palo Alto,
California
|
$114M
|
+$148K
|
+7,356
|
+0.2%
|
|
|
9
|
Acuta Capital Partners
Redwood City,
California
|
$112M
|
-$22.1M
|
-1,100,000
|
-19%
|
|
|
10
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$102M
|
-$12.8M
|
-636,214
|
-13%
|
|
|
11
|
Millennium Management
New York
|
$88.6M
|
+$19.2M
|
+956,801
|
+34%
|
|
|
12
|
Janus Henderson Group
London,
|
$76.2M
|
+$25.8M
|
+1,284,303
|
+66%
|
|
|
13
|
RA Capital Management
Boston,
Massachusetts
|
$73.8M
|
+$62.7M
|
+3,119,778
|
New
|
|
|
14
|
Foresite Capital Management III
Larkspur,
California
|
$60.2M
|
-$3.18M
|
-158,271
|
-6%
|
|
|
15
|
Jennison Associates
New York
|
$50.8M
|
+$707K
|
+35,186
|
+2%
|
|
|
16
|
Victory Capital Management
San Antonio,
Texas
|
$49M
|
+$4.01M
|
+199,320
|
+11%
|
|
|
17
|
Alkeon Capital Management
New York
|
$43.8M
|
+$37.2M
|
+1,850,000
|
New
|
|
|
18
|
Citadel Advisors
Miami,
Florida
|
$40.7M
|
-$2.04M
|
-101,687
|
-6%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$40M
|
+$8.71M
|
+433,359
|
+34%
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$36.8M
|
+$10.3M
|
+510,544
|
+49%
|
|
|
21
|
American Century Companies
Kansas City,
Missouri
|
$36.6M
|
+$31.1M
|
+1,545,044
|
New
|
|
|
22
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$34.1M
|
+$10.2M
|
+505,631
|
+54%
|
|
|
23
|
VOYA Investment Management
Atlanta,
Georgia
|
$31.6M
|
+$25.9M
|
+1,288,515
|
+2,844%
|
|
|
24
|
Nexthera Capital
New York
|
$31.5M
|
+$4.98M
|
+247,694
|
+23%
|
|
|
25
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$30.9M
|
-$5.93M
|
-294,970
|
-18%
|
|
