|
1
|
Avoro Capital Advisors
New York
|
$260M
|
+$15.6M
|
+1,325,000
|
+9%
|
|
|
2
|
|
$146M
|
+$8.69M
|
+736,608
|
+9%
|
|
|
3
|
|
$137M
|
-$18.1M
|
-1,535,089
|
-15%
|
|
|
4
|
Acuta Capital Partners
Redwood City,
California
|
$109M
|
+$145K
|
+12,294
|
+0.2%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$107M
|
+$2.97M
|
+251,530
|
+4%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$103M
|
+$19.4M
|
+1,645,878
|
+35%
|
|
|
7
|
Millennium Management
New York
|
$102M
|
+$39.9M
|
+3,376,764
|
+116%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$87M
|
+$8.42M
|
+713,620
|
+15%
|
|
|
9
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$84.4M
|
+$20.1M
|
+1,705,624
|
+48%
|
|
|
10
|
Fidelity Investments
Boston,
Massachusetts
|
$77.3M
|
-$8.46M
|
-716,400
|
-13%
|
|
|
11
|
Palo Alto Investors
Palo Alto,
California
|
$77.2M
|
+$20.8M
|
+1,763,795
|
+59%
|
|
|
12
|
Citadel Advisors
Miami,
Florida
|
$71.6M
|
+$38.6M
|
+3,270,177
|
+281%
|
|
|
13
|
NEA Management Company
Timonium,
Maryland
|
$44.8M
|
–
|
–
|
–
|
|
|
14
|
Foresite Capital Management III
Larkspur,
California
|
$43.6M
|
+$3.78M
|
+320,633
|
+13%
|
|
|
15
|
Jennison Associates
New York
|
$29.6M
|
+$227K
|
+19,195
|
+1%
|
|
|
16
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$26.2M
|
+$6.11M
|
+517,611
|
+47%
|
|
|
17
|
Ghost Tree Capital
New York
|
$24.9M
|
-$4.83M
|
-408,946
|
-21%
|
|
|
18
|
Janus Henderson Group
London,
|
$24.5M
|
+$17.9M
|
+1,518,335
|
New
|
|
|
19
|
Deerfield Management
New York
|
$21M
|
+$8.48M
|
+718,448
|
+123%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$20.2M
|
-$61.8K
|
-5,234
|
-0.4%
|
|
|
21
|
Victory Capital Management
San Antonio,
Texas
|
$17.9M
|
+$13.1M
|
+1,110,192
|
New
|
|
|
22
|
Foresite Capital Management IV
Larkspur,
California
|
$17.3M
|
+$12.7M
|
+1,073,272
|
New
|
|
|
23
|
Geode Capital Management
Boston,
Massachusetts
|
$16.1M
|
+$996K
|
+84,407
|
+9%
|
|
|
24
|
First Light Asset Management
Edina,
Minnesota
|
$15.3M
|
-$4.33M
|
-367,110
|
-28%
|
|
|
25
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$15.2M
|
-$2.28M
|
-193,394
|
-17%
|
|
