|
1
|
Avoro Capital Advisors
New York
|
$206M
|
+$42.4M
|
+4,251,385
|
+41%
|
|
|
2
|
|
$140M
|
+$50.5M
|
+5,067,858
|
+103%
|
|
|
3
|
|
$116M
|
+$949K
|
+95,208
|
+1%
|
|
|
4
|
Acuta Capital Partners
Redwood City,
California
|
$94.2M
|
+$51.2M
|
+5,137,706
|
+321%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$89.1M
|
+$4.07M
|
+408,370
|
+7%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$76.8M
|
–
|
–
|
–
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$66.4M
|
-$676K
|
-67,832
|
-1%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$65.3M
|
+$1.47M
|
+147,019
|
+3%
|
|
|
9
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$49.2M
|
+$20.9M
|
+2,096,383
|
+147%
|
|
|
10
|
Palo Alto Investors
Palo Alto,
California
|
$42.1M
|
–
|
–
|
–
|
|
|
11
|
Millennium Management
New York
|
$40.6M
|
-$13.1M
|
-1,314,720
|
-31%
|
|
|
12
|
EcoR1 Capital
San Francisco,
California
|
$40M
|
+$28.5M
|
+2,860,019
|
New
|
|
|
13
|
NEA Management Company
Timonium,
Maryland
|
$38.8M
|
+$27.6M
|
+2,772,643
|
New
|
|
|
14
|
Foresite Capital Management III
Larkspur,
California
|
$33.3M
|
+$4.37M
|
+438,517
|
+23%
|
|
|
15
|
Ghost Tree Capital
New York
|
$27.2M
|
+$7.44M
|
+746,946
|
+62%
|
|
|
16
|
Creative Planning
Overland Park,
Kansas
|
$26.2M
|
+$16.9M
|
+1,692,717
|
+945%
|
|
|
17
|
Jennison Associates
New York
|
$25.3M
|
+$7.24M
|
+726,723
|
+67%
|
|
|
18
|
RA Capital Management
Boston,
Massachusetts
|
$20.7M
|
+$14.7M
|
+1,478,742
|
New
|
|
|
19
|
Renaissance Technologies
New York
|
$20.1M
|
+$14.3M
|
+1,436,607
|
New
|
|
|
20
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$19.4M
|
+$9.59M
|
+962,324
|
+227%
|
|
|
21
|
First Light Asset Management
Edina,
Minnesota
|
$18.3M
|
-$7.35M
|
-737,129
|
-36%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$17.5M
|
-$228K
|
-22,840
|
-2%
|
|
|
23
|
Citadel Advisors
Miami,
Florida
|
$16.3M
|
+$11.6M
|
+1,163,007
|
New
|
|
|
24
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$15.8M
|
-$656K
|
-65,799
|
-5%
|
|
|
25
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$15.4M
|
+$11M
|
+1,101,463
|
New
|
|
