|
1
|
Avoro Capital Advisors
New York
|
$518M
|
+$61.7M
|
+3,500,000
|
+17%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$345M
|
+$19.7M
|
+1,114,895
|
+7%
|
|
|
3
|
|
$311M
|
+$8.12M
|
+460,527
|
+3%
|
|
|
4
|
Boxer Capital
San Diego,
California
|
$179M
|
+$26.5M
|
+1,500,000
|
+22%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$144M
|
+$3.38M
|
+191,775
|
+3%
|
|
|
6
|
Palo Alto Investors
Palo Alto,
California
|
$125M
|
-$4.61M
|
-261,125
|
-4%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$123M
|
-$1.36M
|
-77,288
|
-1%
|
|
|
8
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$114M
|
+$2.13M
|
+120,987
|
+2%
|
|
|
9
|
Fidelity Investments
Boston,
Massachusetts
|
$97.7M
|
-$42.3M
|
-2,398,442
|
-34%
|
|
|
10
|
|
$92.5M
|
–
|
–
|
–
|
|
|
11
|
Ameriprise
Minneapolis,
Minnesota
|
$91.9M
|
+$36.1M
|
+2,047,713
|
+89%
|
|
|
12
|
Janus Henderson Group
London,
|
$78.3M
|
-$4.27M
|
-241,845
|
-6%
|
|
|
13
|
Jennison Associates
New York
|
$64M
|
+$4.79M
|
+271,637
|
+10%
|
|
|
14
|
American Century Companies
Kansas City,
Missouri
|
$63.6M
|
-$8.19M
|
-464,496
|
-13%
|
|
|
15
|
Alkeon Capital Management
New York
|
$60.7M
|
+$7.5M
|
+425,000
|
+17%
|
|
|
16
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
$60.3M
|
+$11.8M
|
+669,388
|
+31%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$53.8M
|
+$3.88M
|
+220,086
|
+9%
|
|
|
18
|
Wells Fargo
San Francisco,
California
|
$48.7M
|
+$79.8K
|
+4,524
|
+0.2%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$45M
|
-$878K
|
-49,754
|
-2%
|
|
|
20
|
|
$37.6M
|
+$1.76M
|
+100,000
|
+6%
|
|
|
21
|
Foresite Capital Management III
Larkspur,
California
|
$37M
|
-$3.64M
|
-206,362
|
-11%
|
|
|
22
|
Deerfield Management
New York
|
$36.5M
|
-$26.3M
|
-1,491,382
|
-46%
|
|
|
23
|
Franklin Resources
San Mateo,
California
|
$36.1M
|
+$14.1M
|
+800,000
|
+88%
|
|
|
24
|
|
$35.9M
|
+$12.8M
|
+727,897
|
+75%
|
|
|
25
|
Victory Capital Management
San Antonio,
Texas
|
$34.2M
|
+$28M
|
+1,588,944
|
+5,420%
|
|
