|
1
|
Avoro Capital Advisors
New York
|
$291M
|
+$49.4M
|
+3,285,539
|
+19%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$210M
|
+$5.12M
|
+340,156
|
+2%
|
|
|
3
|
|
$191M
|
+$18.7M
|
+1,239,462
|
+10%
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$176M
|
-$153M
|
-10,191,724
|
-45%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$113M
|
+$16.6M
|
+1,105,388
|
+16%
|
|
|
6
|
Palo Alto Investors
Palo Alto,
California
|
$92.6M
|
+$4.44M
|
+295,200
|
+5%
|
|
|
7
|
Boxer Capital
San Diego,
California
|
$91.1M
|
+$37.1M
|
+2,467,000
|
+60%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$85.3M
|
-$44.5M
|
-2,959,466
|
-32%
|
|
|
9
|
Deerfield Management
New York
|
$69.1M
|
+$17.9M
|
+1,190,600
|
+31%
|
|
|
10
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$65.3M
|
+$10M
|
+666,914
|
+16%
|
|
|
11
|
|
$60.7M
|
–
|
–
|
–
|
|
|
12
|
Janus Henderson Group
London,
|
$54.9M
|
+$1.87M
|
+124,387
|
+3%
|
|
|
13
|
American Century Companies
Kansas City,
Missouri
|
$49.1M
|
+$8.01M
|
+532,471
|
+18%
|
|
|
14
|
Citadel Advisors
Miami,
Florida
|
$44.9M
|
+$47.8M
|
+3,175,235
|
+5,084%
|
|
|
15
|
Jennison Associates
New York
|
$41.7M
|
-$484K
|
-32,179
|
-1%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$31.9M
|
+$3.88M
|
+257,713
|
+13%
|
|
|
17
|
TimesSquare Capital Management
New York
|
$31.1M
|
-$1.06M
|
-70,600
|
-3%
|
|
|
18
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
$30.6M
|
+$2.05M
|
+136,173
|
+7%
|
|
|
19
|
Ameriprise
Minneapolis,
Minnesota
|
$28.1M
|
+$6.82M
|
+453,503
|
+29%
|
|
|
20
|
Alkeon Capital Management
New York
|
$26.9M
|
–
|
–
|
–
|
|
|
21
|
Foresite Capital Management III
Larkspur,
California
|
$26.9M
|
-$6.99M
|
-464,786
|
-19%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$26.6M
|
+$249K
|
+16,557
|
+0.9%
|
|
|
23
|
Wells Fargo
San Francisco,
California
|
$24.3M
|
-$257K
|
-17,064
|
-1%
|
|
|
24
|
|
$20M
|
+$1.39M
|
+92,479
|
+7%
|
|
|
25
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$19.1M
|
+$2.01M
|
+133,795
|
+11%
|
|
