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Structure Therapeutics
GPCR

Overview Fund Activity

170 hedge funds and large institutions have $1.13B invested in Structure Therapeutics in 2025 Q2 according to their latest regulatory filings, with 37 funds opening new positions, 61 increasing their positions, 44 reducing their positions, and 17 closing their positions.

Holders
170
Holders Change
+19
Holders Change %
+12.58%
% of All Funds
2.28%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
37
Increased
61
Reduced
44
Closed
17
Calls
$10.3M
Puts
$8.34M
Net Calls
+$1.93M
Net Calls Change
+$1.18M

Top Buyers

1
BBA
1
Baker Bros. Advisors
New York
$52M
2
DTC
2
Deep Track Capital
Connecticut
$106M
3
O
3
OrbiMed
New York
$24.9M
4
CC
4
Casdin Capital
New York
$25.4M
5
PHAM
5
Pacific Heights Asset Management
California
$9.54M

Top Sellers

1
Capital Research Global Investors
1
Capital Research Global Investors
California
$0
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$102M
3
Fidelity International
3
Fidelity International
Bermuda
$0
4
Wellington Management Group
4
Wellington Management Group
Massachusetts
$143M
5
Federated Hermes
5
Federated Hermes
Pennsylvania
$9.71M
Name Market Value Shares Shares
Change 		Shares
Change %
MIM
26
Monashee Investment Management
Massachusetts
$8.92M 430,000 +137,138 +47%
Invesco
27
Invesco
Georgia
$8.81M 424,548 +30,162 +8%
Aberdeen Group
28
Aberdeen Group
United Kingdom
$8.33M 401,624 +152,725 +61%
Handelsbanken Fonder
29
Handelsbanken Fonder
Sweden
$7.88M 380,000 – –
DM
30
Deerfield Management
New York
$7.74M 373,407 – –
T. Rowe Price Associates
31
T. Rowe Price Associates
Maryland
$7.32M 352,868 -424,305 -55%
BG
32
Bellevue Group
Switzerland
$7.23M 348,527 +126,812 +57%
Point72 Asset Management
33
Point72 Asset Management
Connecticut
$6.84M 330,000 +100,569 +44%
SSA
34
Schonfeld Strategic Advisors
New York
$6.67M 321,591 +321,591 New
ACH
35
ArrowMark Colorado Holdings
Colorado
$6.2M 298,937 +53,751 +22%
HH
36
HSG Holding
Hong Kong
$5.52M 266,062 – –
BlackRock
37
BlackRock
New York
$5.05M 243,334 -323,171 -57%
Goldman Sachs
38
Goldman Sachs
New York
$4.57M 220,174 -104,261 -32%
FCMV
39
Foresite Capital Management VI
California
$4.36M 210,000 -210,000 -50%
PC
40
Pier Capital
Connecticut
$4.12M 198,478 -14,042 -7%
IC
41
Ikarian Capital
Texas
$3.8M 183,085 -81,000 -31%
RAM
42
Readystate Asset Management
Illinois
$3.7M 178,612 -302,629 -63%
WP
43
Woodline Partners
California
$3.66M 176,453 +1,029 +0.6%
Marshall Wace
44
Marshall Wace
United Kingdom
$3.65M 176,060 +145,434 +475%
SCM
45
Silverarc Capital Management
Massachusetts
$3.64M 175,636 -12,433 -7%
NCM
46
Nantahala Capital Management
Connecticut
$3.5M 168,553 – –
Canada Pension Plan Investment Board
47
Canada Pension Plan Investment Board
Ontario, Canada
$3.48M 167,800 +167,800 New
UBS Group
48
UBS Group
Switzerland
$3.17M 152,981 -85,216 -36%
CWM
49
CCG Wealth Management
California
$3.11M 150,000 – –
SFI
50
Susquehanna Fundamental Investments
Pennsylvania
$2.9M 139,717 -18,244 -12%
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