GPCR icon

Structure Therapeutics
GPCR

Overview Fund Activity

172 hedge funds and large institutions have $1.13B invested in Structure Therapeutics in 2025 Q2 according to their latest regulatory filings, with 38 funds opening new positions, 62 increasing their positions, 44 reducing their positions, and 17 closing their positions.

Holders
172
Holders Change
+21
Holders Change %
+13.91%
% of All Funds
2.31%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
38
Increased
62
Reduced
44
Closed
17
Calls
$12.5M
Puts
$10.5M
Net Calls
+$1.95M
Net Calls Change
+$1.2M

Top Buyers

1
BBA
1
Baker Bros. Advisors
New York
$52M
2
DTC
2
Deep Track Capital
Connecticut
$106M
3
O
3
OrbiMed
New York
$24.9M
4
CC
4
Casdin Capital
New York
$25.4M
5
PHAM
5
Pacific Heights Asset Management
California
$9.54M

Top Sellers

1
Capital Research Global Investors
1
Capital Research Global Investors
California
$0
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$102M
3
Fidelity International
3
Fidelity International
Bermuda
$0
4
Wellington Management Group
4
Wellington Management Group
Massachusetts
$143M
5
Federated Hermes
5
Federated Hermes
Pennsylvania
$9.71M
Name Market Value Shares Shares
Change 		Shares
Change %
RPAM
51
Rhenman & Partners Asset Management
Sweden
$2.8M 135,100 +65,100 +93%
FLAM
52
First Light Asset Management
Minnesota
$2.53M 122,226 -10,154 -8%
PE
53
Point72 Europe
United Kingdom
$2.42M 116,697 +26,000 +29%
Renaissance Technologies
54
Renaissance Technologies
New York
$2.32M 111,900 +96,100 +608%
EP
55
Eversept Partners
New York
$2.06M 99,338 +99,338 New
SFM
56
Sphera Funds Management
Israel
$1.99M 95,931 +11,931 +14%
HS
57
HighVista Strategies
Massachusetts
$1.8M 86,621 +69,060 +393%
TI
58
Trexquant Investment
Connecticut
$1.69M 81,588 -38,752 -32%
Susquehanna International Group
59
Susquehanna International Group
Pennsylvania
$1.57M 75,802 +7,635 +11%
PIM
60
Platinum Investment Management
Australia
$1.55M 74,900 – –
Verition Fund Management
61
Verition Fund Management
Connecticut
$1.51M 72,984 +53,402 +273%
CSS
62
Cubist Systematic Strategies
Connecticut
$1.49M 71,690 +16,874 +31%
BPC
63
Banque Pictet & Cie
Switzerland
$1.46M 70,401 -11,365 -14%
JG
64
Jain Global
New York
$1.44M 69,369 +45,730 +193%
BNP Paribas Financial Markets
65
BNP Paribas Financial Markets
France
$1.37M 65,836 +61,318 +1,357%
JF
66
Jump Financial
Illinois
$1.31M 63,234 +32,524 +106%
ETC
67
Exchange Traded Concepts
Oklahoma
$1.28M 61,732 +22,809 +59%
Bank of Montreal
68
Bank of Montreal
Ontario, Canada
$1.22M 58,073 +4,838 +9%
DCM
69
DAFNA Capital Management
California
$1.22M 59,000 – –
Macquarie Group
70
Macquarie Group
Australia
$1.2M 58,000 – –
BFM
71
Boothbay Fund Management
New York
$1.2M 57,622 -19,672 -25%
PHS
72
PFM Health Sciences
California
$1.17M 56,594 +16,194 +40%
Geode Capital Management
73
Geode Capital Management
Massachusetts
$1.12M 54,181 +8,444 +18%
EAM
74
Exome Asset Management
New York
$1.11M 53,744 -49,200 -48%
SAM
75
Sectoral Asset Management
Quebec, Canada
$1.07M 51,369 +17,674 +52%
1 2
3
4 5