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Structure Therapeutics
GPCR

Overview Fund Activity

163 hedge funds and large institutions have $1.65B invested in Structure Therapeutics in 2024 Q4 according to their latest regulatory filings, with 28 funds opening new positions, 65 increasing their positions, 49 reducing their positions, and 23 closing their positions.

Holders
163
Holders Change
+3
Holders Change %
+1.88%
% of All Funds
2.17%
Holding in Top 10
5
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-28.57%
% of All Funds
0.07%
New
28
Increased
65
Reduced
49
Closed
23
Calls
$28.1M
Puts
$17.3M
Net Calls
+$10.8M
Net Calls Change
+$8.67M

Top Buyers

1
DTC
1
Deep Track Capital
Connecticut
$75.9M
2
VPC
2
Vestal Point Capital
New York
$46.8M
3
Marshall Wace
3
Marshall Wace
United Kingdom
$15.8M
4
Ameriprise
4
Ameriprise
Minnesota
$38.5M
5
CCM
5
Camber Capital Management
Massachusetts
$8.14M

Top Sellers

1
OCA
1
Octagon Capital Advisors
New York
$0
2
T. Rowe Price Investment Management
2
T. Rowe Price Investment Management
Maryland
$0
3
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$12.9M
4
APM
4
Avidity Partners Management
Texas
$0
5
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$37.8M
Name Holding Trade Value Shares
Change 		Shares
Change %
Wellington Management Group
1
Wellington Management Group
Massachusetts
$211M +$430K +15,843 +0.2%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$165M -$1.35M -49,698 -0.8%
Janus Henderson Group
3
Janus Henderson Group
United Kingdom
$113M +$5.51M +203,010 +5%
Capital Research Global Investors
4
Capital Research Global Investors
California
$95.9M +$187K +6,891 +0.2%
DTC
5
Deep Track Capital
Connecticut
$75.9M +$42.8M +1,579,492 +129%
DCM
6
Driehaus Capital Management
Illinois
$55.8M -$12.7M -469,020 -19%
Federated Hermes
7
Federated Hermes
Pennsylvania
$55.5M -$9.92M -365,642 -15%
BI
8
BVF Inc
California
$48M -$12.7M -467,569 -21%
VPC
9
Vestal Point Capital
New York
$46.8M +$15.6M +575,000 +50%
Capital International Investors
10
Capital International Investors
California
$43.9M +$2.79M +103,059 +7%
RCM
11
RA Capital Management
Massachusetts
$41.2M -$10.3M -379,354 -20%
Citadel Advisors
12
Citadel Advisors
Florida
$40.1M +$755K +27,841 +2%
Ameriprise
13
Ameriprise
Minnesota
$38.5M +$8.75M +322,601 +29%
T. Rowe Price Associates
14
T. Rowe Price Associates
Maryland
$37.8M -$18.7M -690,381 -33%
Fidelity International
15
Fidelity International
Bermuda
$35.3M -$285K -10,520 -0.8%
RSCM
16
Rock Springs Capital Management
Maryland
$29.3M +$462K +17,053 +2%
TCM
17
TCG Crossover Management
California
$28.8M – – –
Principal Financial Group
18
Principal Financial Group
Iowa
$21.5M +$6.67M +245,775 +45%
Millennium Management
19
Millennium Management
New York
$20.4M -$4.35M -160,438 -18%
Franklin Resources
20
Franklin Resources
California
$20M +$867K +31,984 +5%
LGM
21
Logos Global Management
California
$19M -$14.9M -550,000 -44%
CC
22
Casdin Capital
New York
$19M – – –
O
23
OrbiMed
New York
$17.7M +$7.28M +268,323 +70%
American Century Companies
24
American Century Companies
Missouri
$16.6M +$1.83M +67,325 +12%
BlackRock
25
BlackRock
New York
$16.6M -$1.89M -69,512 -10%
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