GPCR icon

Structure Therapeutics
GPCR

Overview Fund Activity

172 hedge funds and large institutions have $1.13B invested in Structure Therapeutics in 2025 Q2 according to their latest regulatory filings, with 38 funds opening new positions, 62 increasing their positions, 44 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
172
Holders Change
+21
Holders Change %
+13.91%
% of All Funds
2.31%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
38
Increased
62
Reduced
44
Closed
17
Calls
$12.5M
Puts
$10.5M
Net Calls
+$1.95M
Net Calls Change
+$1.2M

Top Buyers

1
BBA
1
Baker Bros. Advisors
New York
$52M
2
DTC
2
Deep Track Capital
Connecticut
$106M
3
O
3
OrbiMed
New York
$24.9M
4
CC
4
Casdin Capital
New York
$25.4M
5
PHAM
5
Pacific Heights Asset Management
California
$9.54M

Top Sellers

1
Capital Research Global Investors
1
Capital Research Global Investors
California
$0
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$102M
3
Fidelity International
3
Fidelity International
Bermuda
$0
4
Wellington Management Group
4
Wellington Management Group
Massachusetts
$143M
5
Federated Hermes
5
Federated Hermes
Pennsylvania
$9.71M
Name Holding Trade Value Shares
Change 		Shares
Change %
Wellington Management Group
1
Wellington Management Group
Massachusetts
$143M -$19M -915,414 -12%
DTC
2
Deep Track Capital
Connecticut
$106M +$21.4M +1,033,917 +25%
Fidelity Investments
3
Fidelity Investments
Massachusetts
$102M -$20.1M -968,742 -16%
Janus Henderson Group
4
Janus Henderson Group
United Kingdom
$94.9M +$4.52M +217,812 +5%
BBA
5
Baker Bros. Advisors
New York
$52M +$44.5M +2,147,202 +594%
BI
6
BVF Inc
California
$36.7M – – –
Capital International Investors
7
Capital International Investors
California
$33.6M -$3.11K -150 -0%
Ameriprise
8
Ameriprise
Minnesota
$32.9M +$2.21M +106,389 +7%
RCM
9
RA Capital Management
Massachusetts
$31.5M – – –
Citadel Advisors
10
Citadel Advisors
Florida
$27.6M +$6.97M +336,139 +34%
CC
11
Casdin Capital
New York
$25.4M +$10.9M +525,000 +75%
Millennium Management
12
Millennium Management
New York
$25.3M +$8.92M +429,896 +54%
VPC
13
Vestal Point Capital
New York
$24.9M -$12.2M -588,990 -33%
O
14
OrbiMed
New York
$24.9M +$11.4M +547,272 +84%
RSCM
15
Rock Springs Capital Management
Maryland
$23.6M +$60.1K +2,900 +0.3%
TCM
16
TCG Crossover Management
California
$22M – – –
Morgan Stanley
17
Morgan Stanley
New York
$19M +$4.66M +224,907 +32%
Principal Financial Group
18
Principal Financial Group
Iowa
$17.7M +$2M +96,495 +13%
LGM
19
Logos Global Management
California
$17.6M +$8.81M +425,000 +100%
Franklin Resources
20
Franklin Resources
California
$15.4M +$33.8K +1,631 +0.2%
DCM
21
Driehaus Capital Management
Illinois
$14M -$12.4M -599,951 -47%
CCM
22
Catalio Capital Management
New York
$13.9M -$711K -34,289 -5%
American Century Companies
23
American Century Companies
Missouri
$10.2M -$394K -19,008 -4%
Federated Hermes
24
Federated Hermes
Pennsylvania
$9.71M -$14.6M -702,648 -60%
PHAM
25
Pacific Heights Asset Management
California
$9.54M +$9.54M +460,000 New
1
2 3 4 5