Structure Therapeutics (GPCR)

• Market cap: $1.16B
• 1 day: -3.4%
• 5 days: -2.32%
• 1 month: 0.4%
• 3 months: -1.8%
• 6 months: -7.3%
• Year to date: -28.34%
• 1 year: -49.5%
• 5 years: -22.31%
• 10 years: -22.31%
• Sector: Healthcare
• Industry: Biotechnology

About: Structure Therapeutics Inc is a clinical-stage biopharmaceutical company developing novel oral small-molecule therapeutics to treat a wide range of chronic diseases with unmet medical needs. Its differentiated technology platform leverages both structure-based drug discovery and expertise in computational chemistry to discover and develop small molecule therapeutics against G-protein coupled receptors (GPCRs). The group operates and manages its business as one reportable and operating segment, which is the business of research and development of medicines that target chronic diseases with unmet medical needs.

Employees: 183

Fund manager confidence

Based on 2025 Q2 regulatory disclosures by fund managers ($100M+ AUM)

200% more funds holding in top 10

Funds holding in top 10: 1 [Q1] → 3 (+2) [Q2]

138% more first-time investments, than exits

New positions opened: 38 | Existing positions closed: 16

62.74% more ownership

Funds ownership: 32.51% [Q1] → 95.25% (+62.74%) [Q2]

41% more repeat investments, than reductions

Existing positions increased: 62 | Existing positions reduced: 44

18% more call options, than puts

Call options by funds: $12.5M | Put options by funds: $10.5M

16% more capital invested

Capital invested by funds: $981M [Q1] → $1.13B (+$153M) [Q2]

15% more funds holding

Funds holding: 150 [Q1] → 172 (+22) [Q2]

Research analyst outlook

4 Wall Street Analysts provided 1 year price targets over the past 3 months

• Low target: $60
• Avg. target: $76
• High target: $90

4 analyst ratings

• positive: 4 100%
• neutral: 0 0%
• negative: 0 0%

HC Wainwright & Co. Ananda Ghosh	$60	Buy Maintained	7 Aug 2025
Guggenheim Seamus Fernandez	$90	Buy Maintained	7 Aug 2025
JMP Securities Jonathan Wolleben	$87	Market Outperform Maintained	7 Aug 2025
Cantor Fitzgerald Prakhar Agrawal	$65	Overweight Reiterated	23 Jun 2025