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Structure Therapeutics

196 hedge funds and large institutions have $3.22B invested in Structure Therapeutics in 2026 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 73 increasing their positions, 58 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

45% more call options, than puts

Call options by funds: $27.4M | Put options by funds: $18.9M

26% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 58

0% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 39

1% less funds holding

Funds holding: 197196 (-1)

14.16% less ownership

Funds ownership: 108.4%94.24% (-14%)

30% less capital invested

Capital invested by funds: $4.58B → $3.22B (-$1.36B)

63% less funds holding in top 10

Funds holding in top 10: 166 (-10)

Holders
196
Holders Change
-1
Holders Change %
-0.51%
% of All Funds
2.41%
Holding in Top 10
6
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-62.5%
% of All Funds
0.07%
New
39
Increased
73
Reduced
58
Closed
39
Calls
$27.4M
Puts
$18.9M
Net Calls
+$8.44M
Net Calls Change
-$35.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$405M -$21.1M -308,802 -4%
Wellington Management Group
2
Wellington Management Group
Massachusetts
$350M +$9.47M +138,303 +2%
ACA
3
Avoro Capital Advisors
New York
$316M
Janus Henderson Group
4
Janus Henderson Group
United Kingdom
$258M +$18.1M +264,833 +5%
DTC
5
Deep Track Capital
Connecticut
$206M +$11.5M +168,066 +4%
BI
6
BVF Inc
California
$167M -$1.35M -19,664 -0.6%
Morgan Stanley
7
Morgan Stanley
New York
$111M +$14.9M +217,623 +10%
T. Rowe Price Associates
8
T. Rowe Price Associates
Maryland
$96.4M +$22.6M +329,558 +20%
Principal Financial Group
9
Principal Financial Group
Iowa
$84.5M +$32.1M +469,554 +37%
DCM
10
Driehaus Capital Management
Illinois
$76M -$4.45M -65,088 -4%
O
11
OrbiMed
New York
$71.1M +$21.5M +313,600 +27%
American Century Companies
12
American Century Companies
Missouri
$69.3M +$63.7M +931,072 +184%
BBA
13
Baker Bros. Advisors
New York
$69M
SL
14
Siren LLC
Connecticut
$64M +$17.1M +250,000 +23%
CC
15
Casdin Capital
New York
$56.6M
CLGM
16
Capitolis Liquid Global Markets
New York
$55.5M +$18.7M +273,000 +31%
AllianceBernstein
17
AllianceBernstein
Tennessee
$44.4M -$14.4M -210,038 -25%
DM
18
Deerfield Management
New York
$37M
PHAM
19
Pacific Heights Asset Management
California
$36.1M +$3.42M +50,000 +7%
RSCM
20
Rock Springs Capital Management
Maryland
$30.9M -$7.39M -108,019 -14%
PBA
21
Paradigm Biocapital Advisors
New York
$26.3M +$37.3M +545,287 New
Franklin Resources
22
Franklin Resources
California
$25.6M -$23.2M -338,987 -39%
LGM
23
Logos Global Management
California
$24.1M -$6.84M -100,000 -17%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
24
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$22.5M
BlackRock
25
BlackRock
New York
$21.3M +$814K +11,893 +3%