SL
GPCR icon

Siren LLC’s Structure Therapeutics GPCR Stock Holding History

Siren LLC’s Portfolio GPCR Stock Details GPCR Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$64M Buy
1,328,698
+250,000
+23% +$17.1M 1.78% 18
2025
Q4 		$75M Buy
1,078,698
+51,887
+5% +$2.12M 2.24% 11
2025
Q3 		$28.8M Buy
+1,026,811
New +$20.5M 1.12% 28

Other funds holding GPCR

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
DTC
Deep Track Capital Greenwich, Connecticut $6.12B AUM 144% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
Principal Financial Group
Principal Financial Group Des Moines, Iowa $187B AUM 18.48% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

Siren LLC's GPCR Position: Q1 2026 in Review

Siren LLC increased its Structure Therapeutics (GPCR) stake by 23% in Q1 2026, buying an estimated $17.1M and bringing the position to 1,328,698 shares worth $64M. The position accounts for 1.78% of the portfolio, ranked #18.

Siren LLC first reported a position in GPCR in Q3 2025 and has held it in 3 quarters since. The position peaked at $75M in Q4 2025. 196 funds tracked by Wall St. Rank hold GPCR as of Q1 2026.

  • Siren LLC held 1,328,698 shares of Structure Therapeutics worth $64M as of Q1 2026.
  • Siren LLC bought 250,000 Structure Therapeutics shares in Q1 2026, an estimated $17.1M.
  • Structure Therapeutics made up 1.78% of Siren LLC's portfolio in Q1 2026, its #18 holding.
  • Siren LLC first reported a position in Structure Therapeutics in Q3 2025 and has held it in 3 quarters since.
  • Siren LLC's Structure Therapeutics position peaked at $75M in Q4 2025.
  • 196 funds tracked by Wall St. Rank held Structure Therapeutics as of Q1 2026.

Based on Siren LLC's 13F filing for Q1 2026, filed 14 May 2026.