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Amicus Therapeutics
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Overview Fund Activity

268 hedge funds and large institutions have $1.83B invested in Amicus Therapeutics in 2025 Q2 according to their latest regulatory filings, with 35 funds opening new positions, 118 increasing their positions, 81 reducing their positions, and 47 closing their positions.

Holders
268
Holders Change
-13
Holders Change %
-4.63%
% of All Funds
3.6%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
35
Increased
118
Reduced
81
Closed
47
Calls
$2.41M
Puts
$1.56M
Net Calls
+$846K
Net Calls Change
+$2.68M

Top Buyers

1
VPC
1
Vestal Point Capital
New York
$68.2M
2
D.E. Shaw & Co
2
D.E. Shaw & Co
New York
$36.5M
3
Millennium Management
3
Millennium Management
New York
$42.5M
4
Assenagon Asset Management
4
Assenagon Asset Management
Luxembourg
$20.2M
5
Qube Research & Technologies (QRT)
5
Qube Research & Technologies (QRT)
United Kingdom
$19.9M

Top Sellers

1
PA
1
Perceptive Advisors
New York
$42.5M
2
RG
2
Redmile Group
California
$6.81M
3
American Century Companies
3
American Century Companies
Missouri
$0
4
NHAS
4
Novo Holdings A/S
Denmark
$0
5
JPMorgan Chase & Co
5
JPMorgan Chase & Co
New York
$12.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
TWP
151
Tempus Wealth Planning
California
$304K +$135K +23,619 +80%
AC
152
AXQ Capital
New Jersey
$290K +$290K +50,548 New
BC
153
Bridgefront Capital
Texas
$286K -$3.55K -619 -1%
KK
154
KLP Kapitalforvaltning
Norway
$284K +$42.4K +7,400 +18%
EP
155
Edgestream Partners
New Jersey
$273K -$61.7K -10,765 -18%
PCM
156
Polymer Capital Management
New York
$267K +$267K +46,562 New
EFM
157
E Fund Management
China
$265K +$130K +22,610 +95%
SSA
158
Schonfeld Strategic Advisors
New York
$263K -$1.51M -263,311 -85%
Brown Advisory
159
Brown Advisory
Maryland
$261K – – –
EC
160
EntryPoint Capital
New York
$261K +$261K +45,496 New
QC
161
Quadrature Capital
United Kingdom
$255K +$255K +44,512 New
TC
162
TwinBeech Capital
New York
$248K -$335K -58,543 -57%
OAM
163
Oxford Asset Management
United Kingdom
$232K +$232K +40,520 New
DnB Asset Management
164
DnB Asset Management
Norway
$225K +$21.3K +3,722 +10%
Walleye Capital
165
Walleye Capital
New York
$209K +$209K +36,418 New
AACP
166
Advantage Alpha Capital Partners
California
$201K +$201K +35,082 New
Franklin Resources
167
Franklin Resources
California
$201K +$56.3K +9,827 +39%
CWM
168
CIBC World Markets
New York
$197K -$176K -30,799 -47%
VT
169
Vise Technologies
New York
$187K +$187K +32,689 New
Comerica Bank
170
Comerica Bank
Texas
$174K +$12.8K +2,240 +8%
Public Employees Retirement Association of Colorado
171
Public Employees Retirement Association of Colorado
Colorado
$173K – – –
SPA
172
Sherbrooke Park Advisers
New York
$169K +$81.7K +14,266 +93%
LCM
173
Legato Capital Management
California
$168K +$44.2K +7,721 +36%
AIP
174
Ameritas Investment Partners
Nebraska
$163K -$13K -2,267 -7%
BC
175
Birchview Capital
Vermont
$160K – – –
5 6
7
8 9