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Amicus Therapeutics
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Overview Fund Activity

270 hedge funds and large institutions have $6.44B invested in Amicus Therapeutics in 2020 Q4 according to their latest regulatory filings, with 49 funds opening new positions, 87 increasing their positions, 99 reducing their positions, and 29 closing their positions.

Holders
270
Holders Change
+20
Holders Change %
+8%
% of All Funds
4.79%
Holding in Top 10
6
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.11%
New
49
Increased
87
Reduced
99
Closed
29
Calls
$85.2M
Puts
$79.1M
Net Calls
+$6.15M
Net Calls Change
-$17.5M

Top Buyers

1
LPC
1
Lone Pine Capital
Connecticut
$154M
2
Wellington Management Group
2
Wellington Management Group
Massachusetts
$234M
3
Macquarie Group
3
Macquarie Group
Australia
$75.9M
4
Morgan Stanley
4
Morgan Stanley
New York
$294M
5
Canada Pension Plan Investment Board
5
Canada Pension Plan Investment Board
Ontario, Canada
$31.2M

Top Sellers

1
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$260M
2
RG
2
Redmile Group
California
$476M
3
ACA
3
Avoro Capital Advisors
New York
$208M
4
ClearBridge Investments
4
ClearBridge Investments
New York
$67.4M
5
UBS AM
5
UBS AM
Illinois
$6.65M
Name Market Value Shares Shares
Change 		Shares
Change %
PA
1
Perceptive Advisors
New York
$580M 25,112,048 -10,000 -0%
Vanguard Group
2
Vanguard Group
Pennsylvania
$551M 23,845,433 +657,866 +3%
BlackRock
3
BlackRock
New York
$505M 21,877,442 +908,634 +4%
RG
4
Redmile Group
California
$476M 20,620,490 -2,455,317 -11%
Morgan Stanley
5
Morgan Stanley
New York
$294M 12,730,857 +1,617,072 +15%
Janus Henderson Group
6
Janus Henderson Group
United Kingdom
$260M 11,247,208 -2,859,051 -20%
Wellington Management Group
7
Wellington Management Group
Massachusetts
$234M 10,136,467 +4,133,312 +69%
ACA
8
Avoro Capital Advisors
New York
$208M 9,000,000 -1,850,000 -17%
JPMorgan Chase & Co
9
JPMorgan Chase & Co
New York
$195M 8,458,917 +158,151 +2%
State Street
10
State Street
Massachusetts
$183M 7,909,391 -1,019,668 -11%
PAI
11
Palo Alto Investors
California
$182M 7,867,114 – –
D.E. Shaw & Co
12
D.E. Shaw & Co
New York
$163M 7,079,596 -264,668 -4%
LPC
13
Lone Pine Capital
Connecticut
$154M 6,678,788 +6,678,788 New
Deutsche Bank
14
Deutsche Bank
Germany
$127M 5,513,614 -491,838 -8%
Jennison Associates
15
Jennison Associates
New York
$109M 4,702,583 -657,222 -12%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$93.7M 4,059,103 +219,012 +6%
Fidelity Investments
17
Fidelity Investments
Massachusetts
$85.5M 3,703,955 -689,233 -16%
Macquarie Group
18
Macquarie Group
Australia
$75.9M 3,287,035 +2,543,281 +342%
Northern Trust
19
Northern Trust
Illinois
$74.5M 3,225,905 -78,592 -2%
Victory Capital Management
20
Victory Capital Management
Texas
$73.7M 3,190,052 -635,449 -17%
Goldman Sachs
21
Goldman Sachs
New York
$68.2M 2,952,906 +415,368 +16%
ClearBridge Investments
22
ClearBridge Investments
New York
$67.4M 2,917,200 -1,320,992 -31%
Norges Bank
23
Norges Bank
Norway
$63.4M 2,747,126 -963,604 -26%
Nuveen Asset Management
24
Nuveen Asset Management
Illinois
$61.4M 2,661,034 -36,009 -1%
AG
25
Artal Group
Luxembourg
$57.7M 2,500,000 -500,000 -17%
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