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Amicus Therapeutics
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Overview Fund Activity

221 hedge funds and large institutions have $3.2B invested in Amicus Therapeutics in 2022 Q3 according to their latest regulatory filings, with 35 funds opening new positions, 75 increasing their positions, 71 reducing their positions, and 22 closing their positions.

Holders
221
Holders Change
+10
Holders Change %
+4.74%
% of All Funds
3.82%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.1%
New
35
Increased
75
Reduced
71
Closed
22
Calls
$8.09M
Puts
$5.04M
Net Calls
+$3.06M
Net Calls Change
-$5.41M

Top Buyers

1
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$309M
2
PAMS
2
Pictet Asset Management (Switzerland)
Switzerland
$36.4M
3
Norges Bank
3
Norges Bank
Norway
$45.5M
4
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
4
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$27.4M
5
Fidelity Investments
5
Fidelity Investments
Massachusetts
$29.2M

Top Sellers

1
Deutsche Bank
1
Deutsche Bank
Germany
$16.3M
2
Wellington Management Group
2
Wellington Management Group
Massachusetts
$84.1M
3
Citadel Advisors
3
Citadel Advisors
Florida
$19.1M
4
State Street
4
State Street
Massachusetts
$126M
5
JPMorgan Chase & Co
5
JPMorgan Chase & Co
New York
$150M
Name Market Value Shares Shares
Change 		Shares
Change %
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$309M 29,552,230 +12,772,089 +76%
PA
2
Perceptive Advisors
New York
$286M 27,372,917 +477,385 +2%
ACA
3
Avoro Capital Advisors
New York
$280M 26,800,000 – –
Vanguard Group
4
Vanguard Group
Pennsylvania
$270M 25,871,062 +138,973 +0.5%
RG
5
Redmile Group
California
$227M 21,719,191 -439,700 -2%
BlackRock
6
BlackRock
New York
$208M 19,898,552 -351,306 -2%
Morgan Stanley
7
Morgan Stanley
New York
$179M 17,183,513 -1,130,067 -6%
JPMorgan Chase & Co
8
JPMorgan Chase & Co
New York
$150M 14,337,705 -1,526,402 -10%
State Street
9
State Street
Massachusetts
$126M 12,022,212 -1,896,103 -14%
PAI
10
Palo Alto Investors
California
$103M 9,847,774 – –
Wellington Management Group
11
Wellington Management Group
Massachusetts
$84.1M 8,056,375 -2,968,369 -27%
Macquarie Group
12
Macquarie Group
Australia
$71.8M 6,877,761 +110,515 +2%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$49.3M 4,722,886 +63,632 +1%
Norges Bank
14
Norges Bank
Norway
$45.5M 4,356,740 +1,511,838 +53%
AG
15
Artal Group
Luxembourg
$41.8M 4,000,000 – –
Fiera Capital (Canada)
16
Fiera Capital (Canada)
Quebec, Canada
$38.1M 4,016,555 -66,317 -2%
PAMS
17
Pictet Asset Management (Switzerland)
Switzerland
$36.4M 3,485,302 +2,842,220 +442%
D.E. Shaw & Co
18
D.E. Shaw & Co
New York
$30.3M 2,903,496 -65,240 -2%
Fidelity Investments
19
Fidelity Investments
Massachusetts
$29.2M 2,794,068 +744,451 +36%
Northern Trust
20
Northern Trust
Illinois
$27.8M 2,663,688 -30,413 -1%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
21
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$27.4M 2,626,600 +884,400 +51%
BC
22
Boxer Capital
California
$24.3M 2,325,000 – –
NHAS
23
Novo Holdings A/S
Denmark
$21.9M 2,100,000 -535,000 -20%
William Blair Investment Management
24
William Blair Investment Management
Illinois
$21.8M 2,085,364 -462,242 -18%
Bank of America
25
Bank of America
North Carolina
$21.6M 2,064,445 +107,592 +5%
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