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Amicus Therapeutics
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Overview Fund Activity

281 hedge funds and large institutions have $2.53B invested in Amicus Therapeutics in 2025 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 113 increasing their positions, 86 reducing their positions, and 41 closing their positions.

Holders
281
Holders Change
-5
Holders Change %
-1.75%
% of All Funds
3.82%
Holding in Top 10
5
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+25%
% of All Funds
0.07%
New
41
Increased
113
Reduced
86
Closed
41
Calls
$3.21M
Puts
$5.05M
Net Calls
-$1.84M
Net Calls Change
-$1.73M

Top Buyers

1
NL
1
Nuveen LLC
North Carolina
$28.7M
2
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$24.4M
3
Millennium Management
3
Millennium Management
New York
$27.4M
4
RG
4
Redmile Group
California
$77.8M
5
Bank of America
5
Bank of America
North Carolina
$45.7M

Top Sellers

1
Norges Bank
1
Norges Bank
Norway
$0
2
Fiera Capital (Canada)
2
Fiera Capital (Canada)
Quebec, Canada
$0
3
PA
3
Perceptive Advisors
New York
$175M
4
ACA
4
Avoro Capital Advisors
New York
$167M
5
JPMorgan Chase & Co
5
JPMorgan Chase & Co
New York
$39.9M
Name Market Value Shares Shares
Change 		Shares
Change %
Wellington Management Group
1
Wellington Management Group
Massachusetts
$238M 29,200,617 +738,623 +3%
Vanguard Group
2
Vanguard Group
Pennsylvania
$237M 29,050,621 -208,342 -0.7%
BlackRock
3
BlackRock
New York
$227M 27,823,772 -83,773 -0.3%
PA
4
Perceptive Advisors
New York
$175M 21,464,527 -2,781,425 -11%
ACA
5
Avoro Capital Advisors
New York
$167M 20,500,000 -2,675,000 -12%
William Blair Investment Management
6
William Blair Investment Management
Illinois
$121M 14,778,651 -819,047 -5%
RG
7
Redmile Group
California
$77.8M 9,533,669 +2,478,779 +35%
State Street
8
State Street
Massachusetts
$77.7M 9,519,019 -842,209 -8%
Citadel Advisors
9
Citadel Advisors
Florida
$64M 7,839,543 -400,406 -5%
PAI
10
Palo Alto Investors
California
$59.9M 7,345,002 -317,477 -4%
Macquarie Group
11
Macquarie Group
Australia
$55.6M 6,815,082 +187,060 +3%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$55.2M 6,763,767 +152,835 +2%
Bank of America
13
Bank of America
North Carolina
$45.7M 5,599,679 +1,562,350 +39%
JPMorgan Chase & Co
14
JPMorgan Chase & Co
New York
$39.9M 4,894,284 -2,319,966 -32%
VPC
15
Vestal Point Capital
New York
$34.9M 4,275,000 +925,000 +28%
American Century Companies
16
American Century Companies
Missouri
$31.8M 3,899,228 -3,204 -0.1%
NL
17
Nuveen LLC
North Carolina
$28.7M 3,522,217 +3,522,217 New
Janus Henderson Group
18
Janus Henderson Group
United Kingdom
$28M 3,321,153 -73,905 -2%
Northern Trust
19
Northern Trust
Illinois
$27.5M 3,375,126 +3,487 +0.1%
Millennium Management
20
Millennium Management
New York
$27.4M 3,359,389 +2,902,375 +635%
Massachusetts Financial Services
21
Massachusetts Financial Services
Massachusetts
$26.7M 3,276,371 +8,996 +0.3%
Point72 Asset Management
22
Point72 Asset Management
Connecticut
$24.4M 2,985,108 +2,985,108 New
NHAS
23
Novo Holdings A/S
Denmark
$22.4M 2,750,000 +250,000 +10%
Goldman Sachs
24
Goldman Sachs
New York
$22.1M 2,703,577 +194,213 +8%
Invesco
25
Invesco
Georgia
$21.7M 2,661,394 +105,856 +4%
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