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Amicus Therapeutics
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Overview Fund Activity

268 hedge funds and large institutions have $1.83B invested in Amicus Therapeutics in 2025 Q2 according to their latest regulatory filings, with 35 funds opening new positions, 118 increasing their positions, 81 reducing their positions, and 47 closing their positions.

Holders
268
Holders Change
-13
Holders Change %
-4.63%
% of All Funds
3.6%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
35
Increased
118
Reduced
81
Closed
47
Calls
$2.41M
Puts
$1.56M
Net Calls
+$846K
Net Calls Change
+$2.68M

Top Buyers

1
VPC
1
Vestal Point Capital
New York
$68.2M
2
D.E. Shaw & Co
2
D.E. Shaw & Co
New York
$36.5M
3
Millennium Management
3
Millennium Management
New York
$42.5M
4
Assenagon Asset Management
4
Assenagon Asset Management
Luxembourg
$20.2M
5
Qube Research & Technologies (QRT)
5
Qube Research & Technologies (QRT)
United Kingdom
$19.9M

Top Sellers

1
PA
1
Perceptive Advisors
New York
$42.5M
2
RG
2
Redmile Group
California
$6.81M
3
American Century Companies
3
American Century Companies
Missouri
$0
4
NHAS
4
Novo Holdings A/S
Denmark
$0
5
JPMorgan Chase & Co
5
JPMorgan Chase & Co
New York
$12.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
Wolverine Trading
176
Wolverine Trading
Illinois
$157K -$57.6K -9,712 -27%
Allspring Global Investments
177
Allspring Global Investments
North Carolina
$146K +$3.15K +540 +2%
Bank of Montreal
178
Bank of Montreal
Ontario, Canada
$144K +$144K +25,058 New
LPL Financial
179
LPL Financial
California
$140K +$73.1K +12,752 +109%
TRCT
180
Tower Research Capital (TRC)
New York
$138K +$111K +19,393 +415%
GC
181
Grimes & Company
Massachusetts
$137K +$4.11K +717 +3%
VA
182
Vident Advisory
Georgia
$130K +$58.6K +10,230 +82%
Truist Financial
183
Truist Financial
North Carolina
$129K -$14.2K -2,471 -10%
WI
184
WrapManager Inc
California
$127K +$37.1K +6,475 +41%
DO
185
denkapparat Operations
Germany
$125K – – –
SI
186
Stephens Inc
Arkansas
$124K +$46.1K +8,050 +59%
X
187
Xponance
Pennsylvania
$124K -$3.19K -557 -3%
Group One Trading
188
Group One Trading
Illinois
$117K +$27.5K +4,806 +31%
Principal Financial Group
189
Principal Financial Group
Iowa
$113K -$20.7K -3,613 -15%
VPIM
190
Vanguard Personalized Indexing Management
California
$102K +$39.7K +6,932 +63%
NSEDCP
191
NJ State Employees Deferred Compensation Plan
New Jersey
$97.4K – – –
CL
192
Choreo LLC
Illinois
$92.1K +$92.1K +16,070 New
FCM
193
Farallon Capital Management
California
$91.7K – – –
Royal Bank of Canada
194
Royal Bank of Canada
Ontario, Canada
$88K -$16.2K -2,829 -16%
Marshall Wace
195
Marshall Wace
United Kingdom
$86.3K -$1.04M -181,051 -92%
FA
196
Faithward Advisors
Pennsylvania
$82.6K +$82.6K +14,420 New
RS
197
R Squared
Hong Kong
$81.3K +$81.3K +14,188 New
Cetera Investment Advisers
198
Cetera Investment Advisers
Illinois
$79.2K +$79.2K +13,824 New
1C
199
111 Capital
France
$76.5K +$76.5K +13,355 New
MFIM
200
Mesirow Financial Investment Management
Illinois
$74.5K – – –
6 7
8
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