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Amicus Therapeutics
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Overview Fund Activity

268 hedge funds and large institutions have $1.83B invested in Amicus Therapeutics in 2025 Q2 according to their latest regulatory filings, with 35 funds opening new positions, 118 increasing their positions, 81 reducing their positions, and 47 closing their positions.

Holders
268
Holders Change
-13
Holders Change %
-4.63%
% of All Funds
3.6%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
35
Increased
118
Reduced
81
Closed
47
Calls
$2.41M
Puts
$1.56M
Net Calls
+$846K
Net Calls Change
+$2.68M

Top Buyers

1
VPC
1
Vestal Point Capital
New York
$68.2M
2
D.E. Shaw & Co
2
D.E. Shaw & Co
New York
$36.5M
3
Millennium Management
3
Millennium Management
New York
$42.5M
4
Assenagon Asset Management
4
Assenagon Asset Management
Luxembourg
$20.2M
5
Qube Research & Technologies (QRT)
5
Qube Research & Technologies (QRT)
United Kingdom
$19.9M

Top Sellers

1
PA
1
Perceptive Advisors
New York
$42.5M
2
RG
2
Redmile Group
California
$6.81M
3
American Century Companies
3
American Century Companies
Missouri
$0
4
NHAS
4
Novo Holdings A/S
Denmark
$0
5
JPMorgan Chase & Co
5
JPMorgan Chase & Co
New York
$12.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
Mirae Asset Global Investments
201
Mirae Asset Global Investments
South Korea
$68.2K +$9.25K +1,614 +16%
SG Americas Securities
202
SG Americas Securities
New York
$67K -$510K -89,258 -88%
EM
203
ELCO Management
New York
$65.4K -$57.4K -10,026 -47%
Sumitomo Mitsui Trust Group
204
Sumitomo Mitsui Trust Group
Japan
$64.5K +$64.5K +11,250 New
I
205
InceptionR
California
$61K +$61K +10,649 New
AB
206
Amalgamated Bank
New York
$59K – – –
KBC Group
207
KBC Group
Belgium
$58K – – –
CM
208
Caption Management
Oklahoma
$55.6K -$917K -159,951 -94%
C
209
Covestor
United Kingdom
$54K +$19.4K +3,363 +56%
Carson Wealth (CWM LLC)
210
Carson Wealth (CWM LLC)
Nebraska
$54K +$43.1K +7,502 +396%
Raymond James Financial
211
Raymond James Financial
Florida
$47.6K -$12.7K -2,208 -21%
GFM
212
GF Fund Management
China
$43.8K – – –
TLCM
213
Twin Lakes Capital Management
California
$34.4K – – –
KOCAA
214
Knights of Columbus Asset Advisors
Connecticut
$33.5K – – –
Simplex Trading
215
Simplex Trading
Illinois
$29K -$331K -59,404 -92%
VEA
216
Virtus ETF Advisers
New York
$25.9K -$81K -14,129 -76%
EWA
217
EverSource Wealth Advisors
Alabama
$25.5K +$21.1K +3,677 +473%
Osaic Holdings
218
Osaic Holdings
Arizona
$24.2K +$19K +2,734 +366%
VanEck Associates
219
VanEck Associates
New York
$24K – – –
PA
220
Parallel Advisors
California
$23.5K +$13.6K +2,377 +137%
AF
221
Allworth Financial
California
$19.7K +$18.6K +3,245 +1,735%
Lazard Asset Management
222
Lazard Asset Management
New York
$19K -$39.9K -7,326 -68%
Nisa Investment Advisors
223
Nisa Investment Advisors
Missouri
$16.9K -$20.5K -3,572 -55%
OSNBOA
224
Old Second National Bank of Aurora
Illinois
$13.8K – – –
MCM
225
MAI Capital Management
Ohio
$12.8K -$1.43K -250 -10%
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9
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