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Amylyx Pharmaceuticals
AMLX

Overview Fund Activity

129 hedge funds and large institutions have $523M invested in Amylyx Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 37 increasing their positions, 36 reducing their positions, and 36 closing their positions.

Holders
129
Holders Change
-5
Holders Change %
-3.73%
% of All Funds
1.73%
Holding in Top 10
6
Holding in Top 10 Change
+5
Holding in Top 10 Change %
+500%
% of All Funds
0.08%
New
32
Increased
37
Reduced
36
Closed
36
Calls
$568K
Puts
$17K
Net Calls
+$551K
Net Calls Change
+$633K

Top Buyers

1
Point72 Asset Management
1
Point72 Asset Management
Connecticut
$29.1M
2
BlackRock
2
BlackRock
New York
$35.3M
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$56.4M
4
Fidelity Investments
4
Fidelity Investments
Massachusetts
$19.5M
5
DCM
5
Driehaus Capital Management
Illinois
$8.11M

Top Sellers

1
Aberdeen Group
1
Aberdeen Group
United Kingdom
$4.73M
2
Millennium Management
2
Millennium Management
New York
$9.69M
3
Citadel Advisors
3
Citadel Advisors
Florida
$7.97M
4
Goldman Sachs
4
Goldman Sachs
New York
$8.32M
5
BCM
5
Boxer Capital Management
California
$7.85M
Name Market Value Shares Shares
Change 		Shares
Change %
IIM
76
INTECH Investment Management
Florida
$233K 36,315 +36,315 New
GC
77
Guggenheim Capital
Illinois
$229K 35,752 -2,044 -5%
GCM
78
Graham Capital Management
Connecticut
$219K 34,153 +34,153 New
Citigroup
79
Citigroup
New York
$199K 31,098 -432,142 -93%
AllianceBernstein
80
AllianceBernstein
Tennessee
$196K 30,600 +30,600 New
QC
81
Quadrature Capital
United Kingdom
$188K 29,430 +16,686 +131%
Manulife (Manufacturers Life Insurance)
82
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$167K 25,999 +25,999 New
Group One Trading
83
Group One Trading
Illinois
$166K 25,856 -17,378 -40%
BCM
84
Bridgeway Capital Management
Texas
$165K 25,700 -130,000 -83%
Los Angeles Capital Management
85
Los Angeles Capital Management
California
$149K 23,320 +23,320 New
New York State Common Retirement Fund
86
New York State Common Retirement Fund
New York
$140K 21,900 +21,900 New
PCM
87
Parsons Capital Management
Rhode Island
$139K 21,645 – –
VPIM
88
Vanguard Personalized Indexing Management
California
$135K 21,123 -633 -3%
PPWP
89
Premier Path Wealth Partners
New Jersey
$130K 20,265 – –
MG
90
Marex Group
$128K 20,000 +20,000 New
Brown Advisory
91
Brown Advisory
Maryland
$128K 19,930 – –
VOYA Investment Management
92
VOYA Investment Management
Georgia
$125K 19,476 +19,476 New
CUAMC
93
China Universal Asset Management Company
China
$115K 17,904 +716 +4%
ProShare Advisors
94
ProShare Advisors
Maryland
$113K 17,551 +17,551 New
PFSRSONJ
95
Police & Firemen's Retirement System of New Jersey
New Jersey
$103K 15,992 +15,992 New
Prudential Financial
96
Prudential Financial
New Jersey
$100K 15,620 +420 +3%
Royal Bank of Canada
97
Royal Bank of Canada
Ontario, Canada
$78K 12,133 +283 +2%
Tudor Investment Corp
98
Tudor Investment Corp
Connecticut
$77.4K 12,073 -21,355 -64%
VFA
99
Valeo Financial Advisors
Indiana
$64.1K 10,000 – –
TRCT
100
Tower Research Capital (TRC)
New York
$47.9K 7,467 +664 +10%
2 3
4
5 6