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Amylyx Pharmaceuticals
AMLX

Overview Fund Activity

129 hedge funds and large institutions have $523M invested in Amylyx Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 37 increasing their positions, 36 reducing their positions, and 36 closing their positions.

Holders
129
Holders Change
-5
Holders Change %
-3.73%
% of All Funds
1.73%
Holding in Top 10
6
Holding in Top 10 Change
+5
Holding in Top 10 Change %
+500%
% of All Funds
0.08%
New
32
Increased
37
Reduced
36
Closed
36
Calls
$568K
Puts
$17K
Net Calls
+$551K
Net Calls Change
+$633K

Top Buyers

1
Point72 Asset Management
1
Point72 Asset Management
Connecticut
$29.1M
2
BlackRock
2
BlackRock
New York
$35.3M
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$56.4M
4
Fidelity Investments
4
Fidelity Investments
Massachusetts
$19.5M
5
DCM
5
Driehaus Capital Management
Illinois
$8.11M

Top Sellers

1
Aberdeen Group
1
Aberdeen Group
United Kingdom
$4.73M
2
Millennium Management
2
Millennium Management
New York
$9.69M
3
Citadel Advisors
3
Citadel Advisors
Florida
$7.97M
4
Goldman Sachs
4
Goldman Sachs
New York
$8.32M
5
BCM
5
Boxer Capital Management
California
$7.85M
Name Market Value Shares Shares
Change 		Shares
Change %
NL
51
Nuveen LLC
North Carolina
$997K 155,536 +155,536 New
D.E. Shaw & Co
52
D.E. Shaw & Co
New York
$971K 151,502 -118,504 -44%
Bank of New York Mellon
53
Bank of New York Mellon
New York
$967K 150,837 +150,837 New
Bank of Montreal
54
Bank of Montreal
Ontario, Canada
$920K 143,512 – –
American Century Companies
55
American Century Companies
Missouri
$861K 134,380 +27,366 +26%
Barclays
56
Barclays
United Kingdom
$835K 130,274 -7,131 -5%
CSS
57
Cubist Systematic Strategies
Connecticut
$790K 123,242 +40,112 +48%
AI
58
Allostery Investments
Connecticut
$770K 120,119 -145,980 -55%
Susquehanna International Group
59
Susquehanna International Group
Pennsylvania
$711K 110,846 -1,360,079 -92%
RhumbLine Advisers
60
RhumbLine Advisers
Massachusetts
$645K 100,576 +100,576 New
TCM
61
Tang Capital Management
California
$641K 100,000 – –
EI
62
EAM Investors
California
$641K 99,960 +99,960 New
Ameriprise
63
Ameriprise
Minnesota
$610K 95,219 +82,414 +644%
KCM
64
Kennondale Capital Management
Virginia
$610K 95,165 -107,578 -53%
T. Rowe Price Associates
65
T. Rowe Price Associates
Maryland
$586K 91,392 +33,692 +58%
JPMorgan Chase & Co
66
JPMorgan Chase & Co
New York
$564K 87,989 +33,920 +63%
HWAM
67
Hennion & Walsh Asset Management
New Jersey
$364K 56,831 -26,405 -32%
CF
68
Cantor Fitzgerald
New York
$321K 50,000 -50,000 -50%
Mariner
69
Mariner
Kansas
$312K 48,668 -2,238 -4%
JF
70
Jump Financial
Illinois
$306K 47,800 +47,800 New
CC
71
Centiva Capital
New York
$291K 45,464 +17,242 +61%
MIM
72
MetLife Investment Management
New Jersey
$275K 42,929 +42,929 New
Squarepoint
73
Squarepoint
New York
$261K 40,643 -35,206 -46%
Wells Fargo
74
Wells Fargo
California
$244K 38,101 +37,801 +12,600%
Mirae Asset Global ETFs Holdings
75
Mirae Asset Global ETFs Holdings
Hong Kong
$243K 37,987 +37,987 New
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