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Amylyx Pharmaceuticals
AMLX

Overview Fund Activity

130 hedge funds and large institutions have $524M invested in Amylyx Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 37 increasing their positions, 37 reducing their positions, and 36 closing their positions.

Holders
130
Holders Change
-4
Holders Change %
-2.99%
% of All Funds
1.74%
Holding in Top 10
6
Holding in Top 10 Change
+5
Holding in Top 10 Change %
+500%
% of All Funds
0.08%
New
32
Increased
37
Reduced
37
Closed
36
Calls
$1.48M
Puts
$103K
Net Calls
+$1.38M
Net Calls Change
+$1.46M

Top Buyers

1
Point72 Asset Management
1
Point72 Asset Management
Connecticut
$29.1M
2
BlackRock
2
BlackRock
New York
$35.3M
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$56.4M
4
Fidelity Investments
4
Fidelity Investments
Massachusetts
$19.5M
5
DCM
5
Driehaus Capital Management
Illinois
$8.11M

Top Sellers

1
Aberdeen Group
1
Aberdeen Group
United Kingdom
$4.73M
2
Millennium Management
2
Millennium Management
New York
$9.69M
3
Citadel Advisors
3
Citadel Advisors
Florida
$7.97M
4
Susquehanna International Group
4
Susquehanna International Group
Pennsylvania
$711K
5
Goldman Sachs
5
Goldman Sachs
New York
$8.32M
Name Holding Trade Value Shares
Change 		Shares
Change %
PHS
26
PFM Health Sciences
California
$4.69M -$653K -101,879 -12%
PHP
27
Parkman Healthcare Partners
Connecticut
$4.17M +$4.17M +650,000 New
SSA
28
Schonfeld Strategic Advisors
New York
$4.14M +$3.39M +529,303 +452%
Deutsche Bank
29
Deutsche Bank
Germany
$3.95M +$295K +46,062 +8%
Charles Schwab
30
Charles Schwab
California
$3.77M +$1.38M +215,558 +58%
Invesco
31
Invesco
Georgia
$3.76M +$3.47M +541,189 +1,184%
Acadian Asset Management
32
Acadian Asset Management
Massachusetts
$3.65M +$2.09M +326,976 +135%
Two Sigma Investments
33
Two Sigma Investments
New York
$3.58M -$1.3M -203,207 -27%
RSCM
34
Rock Springs Capital Management
Maryland
$3.2M +$1M +156,536 +46%
Morgan Stanley
35
Morgan Stanley
New York
$3.12M +$80K +12,475 +3%
Two Sigma Advisers
36
Two Sigma Advisers
New York
$3.01M -$1.15M -179,800 -28%
Bank of America
37
Bank of America
North Carolina
$2.9M -$2.2M -342,546 -43%
Qube Research & Technologies (QRT)
38
Qube Research & Technologies (QRT)
United Kingdom
$2.81M -$3.24M -504,865 -54%
Renaissance Technologies
39
Renaissance Technologies
New York
$2.54M -$762K -118,900 -23%
Dimensional Fund Advisors
40
Dimensional Fund Advisors
Texas
$2.4M +$1.6M +250,163 +202%
O
41
OrbiMed
New York
$2.01M -$223K -34,800 -10%
Wellington Management Group
42
Wellington Management Group
Massachusetts
$1.85M -$13.2K -2,064 -0.7%
AWG
43
Alpha Wave Global
New York
$1.77M +$567K +88,531 +47%
JGC
44
J. Goldman & Co
New York
$1.66M +$1.66M +258,600 New
YIH
45
Y-Intercept (HK)
Hong Kong
$1.54M +$1.54M +240,379 New
TAM
46
TFG Asset Management
Cayman Islands
$1.4M +$1.4M +218,750 New
AC
47
Aldebaran Capital
Indiana
$1.4M -$266K -41,426 -16%
Federated Hermes
48
Federated Hermes
Pennsylvania
$1.31M +$7.34K +1,145 +0.6%
Jane Street
49
Jane Street
New York
$1.2M -$924K -144,199 -44%
GCP
50
GSA Capital Partners
United Kingdom
$1.09M +$945K +147,448 +639%
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