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Amylyx Pharmaceuticals
AMLX

Overview Fund Activity

129 hedge funds and large institutions have $523M invested in Amylyx Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 37 increasing their positions, 36 reducing their positions, and 36 closing their positions.

Holders
129
Holders Change
-5
Holders Change %
-3.73%
% of All Funds
1.73%
Holding in Top 10
6
Holding in Top 10 Change
+5
Holding in Top 10 Change %
+500%
% of All Funds
0.08%
New
32
Increased
37
Reduced
36
Closed
36
Calls
$568K
Puts
$17K
Net Calls
+$551K
Net Calls Change
+$633K

Top Buyers

1
Point72 Asset Management
1
Point72 Asset Management
Connecticut
$29.1M
2
BlackRock
2
BlackRock
New York
$35.3M
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$56.4M
4
Fidelity Investments
4
Fidelity Investments
Massachusetts
$19.5M
5
DCM
5
Driehaus Capital Management
Illinois
$8.11M

Top Sellers

1
Aberdeen Group
1
Aberdeen Group
United Kingdom
$4.73M
2
Millennium Management
2
Millennium Management
New York
$9.69M
3
Citadel Advisors
3
Citadel Advisors
Florida
$7.97M
4
Goldman Sachs
4
Goldman Sachs
New York
$8.32M
5
BCM
5
Boxer Capital Management
California
$7.85M
Name Market Value Shares Shares
Change 		Shares
Change %
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$56.4M 8,800,000 +3,102,395 +54%
PA
2
Perceptive Advisors
New York
$50.7M 7,902,365 +28,017 +0.4%
TCM
3
TCG Crossover Management
California
$38.1M 5,943,812 – –
BlackRock
4
BlackRock
New York
$35.3M 5,510,189 +3,122,780 +131%
Point72 Asset Management
5
Point72 Asset Management
Connecticut
$29.1M 4,536,266 +3,619,300 +395%
Vanguard Group
6
Vanguard Group
Pennsylvania
$28.8M 4,498,028 +381,516 +9%
SVCM
7
Saturn V Capital Management
Texas
$20.9M 3,260,570 +834,134 +34%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$19.5M 3,048,019 +1,890,031 +163%
NCM
9
Nantahala Capital Management
Connecticut
$18.8M 2,934,405 – –
6CM
10
683 Capital Management
New York
$13.8M 2,160,000 -251,400 -10%
AC
11
Almitas Capital
California
$13.6M 2,122,597 – –
GPP
12
Great Point Partners
Connecticut
$12.8M 2,000,000 +188,004 +10%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$10.9M 1,692,413 +886,252 +110%
Millennium Management
14
Millennium Management
New York
$9.69M 1,512,058 -1,569,795 -51%
Goldman Sachs
15
Goldman Sachs
New York
$8.32M 1,297,982 -704,979 -35%
DCM
16
Driehaus Capital Management
Illinois
$8.11M 1,264,997 +1,264,997 New
UBS Group
17
UBS Group
Switzerland
$8.03M 1,253,344 -135,083 -10%
Citadel Advisors
18
Citadel Advisors
Florida
$7.97M 1,242,927 -1,514,849 -55%
BCM
19
Boxer Capital Management
California
$7.85M 1,225,000 -525,000 -30%
ACM
20
ADAR1 Capital Management
Texas
$7.72M 1,205,101 -266,486 -18%
WP
21
Woodline Partners
California
$7.69M 1,200,290 -409,157 -25%
Connor, Clark & Lunn Investment Management (CC&L)
22
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$7.4M 1,154,485 -45,206 -4%
State Street
23
State Street
Massachusetts
$6.47M 1,008,909 +747,126 +285%
Northern Trust
24
Northern Trust
Illinois
$5.26M 820,164 +680,832 +489%
Aberdeen Group
25
Aberdeen Group
United Kingdom
$4.73M 738,657 -1,691,701 -70%
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