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Amylyx Pharmaceuticals

143 hedge funds and large institutions have $141M invested in Amylyx Pharmaceuticals in 2024 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 56 increasing their positions, 48 reducing their positions, and 60 closing their positions.

New
Increased
Maintained
Reduced
Closed

94% more call options, than puts

Call options by funds: $20.5M | Put options by funds: $10.6M

17% more repeat investments, than reductions

Existing positions increased: 56 | Existing positions reduced: 48

20% less funds holding

Funds holding: 178143 (-35)

20.41% less ownership

Funds ownership: 93.47%73.06% (-20%)

58% less first-time investments, than exits

New positions opened: 25 | Existing positions closed: 60

85% less capital invested

Capital invested by funds: $929M → $141M (-$788M)

100% less funds holding in top 10

Funds holding in top 10: 40 (-4)

Holders
143
Holders Change
-35
Holders Change %
-19.66%
% of All Funds
2.06%
Holding in Top 10
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-100%
% of All Funds
New
25
Increased
56
Reduced
48
Closed
60
Calls
$20.5M
Puts
$10.6M
Net Calls
+$9.95M
Net Calls Change
+$9.39M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$15.2M +$949K +72,573 +1%
BlackRock
2
BlackRock
New York
$12.7M +$6.18M +472,388 +12%
Goldman Sachs
3
Goldman Sachs
New York
$8.36M +$22.1M +1,686,325 +134%
Millennium Management
4
Millennium Management
New York
$7.02M +$2.6M +198,812 +9%
Morgan Stanley
5
Morgan Stanley
New York
$5.88M -$47M -3,589,833 -63%
State Street
6
State Street
Massachusetts
$5.85M +$8.09M +618,640 +43%
Franklin Resources
7
Franklin Resources
California
$5.27M +$6.94M +530,885 +40%
BC
8
Boxer Capital
California
$4.26M +$19.6M +1,500,000 New
Two Sigma Investments
9
Two Sigma Investments
New York
$4.07M +$18.2M +1,389,065 +3,171%
Citadel Advisors
10
Citadel Advisors
Florida
$3.78M -$11.9M -910,501 -41%
FCM
11
Farallon Capital Management
California
$3.27M +$15M +1,150,221 New
Geode Capital Management
12
Geode Capital Management
Massachusetts
$3.03M +$465K +35,529 +3%
D.E. Shaw & Co
13
D.E. Shaw & Co
New York
$2.96M +$6.48M +495,618 +91%
Jane Street
14
Jane Street
New York
$2.92M -$1.69M -129,545 -11%
RSCM
15
Rock Springs Capital Management
Maryland
$2.87M +$6.23M +476,400 +89%
Alyeska Investment Group
16
Alyeska Investment Group
Illinois
$2.86M +$13.2M +1,008,607 New
T. Rowe Price Associates
17
T. Rowe Price Associates
Maryland
$2.76M +$991K +75,775 +8%
Qube Research & Technologies (QRT)
18
Qube Research & Technologies (QRT)
United Kingdom
$2.68M +$6.04M +461,464 +96%
Citigroup
19
Citigroup
New York
$2.6M +$6.89M +527,063 +136%
Two Sigma Advisers
20
Two Sigma Advisers
New York
$2.27M +$10.4M +798,900 New
Deutsche Bank
21
Deutsche Bank
Germany
$2.15M -$1.27M -96,831 -11%
Renaissance Technologies
22
Renaissance Technologies
New York
$2M +$8.28M +633,312 +888%
Connor, Clark & Lunn Investment Management (CC&L)
23
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.5M +$3.53M +270,082 +105%
GCM
24
Graham Capital Management
Connecticut
$1.49M +$6.86M +524,627 New
WP
25
Woodline Partners
California
$1.49M +$693K +52,971 +11%

AMLX Hedge Fund Activity: Q1 2024 in Review

143 of the 6,942 institutional investors tracked by Wall St. Rank reported a position in Amylyx Pharmaceuticals (AMLX) for Q1 2024, worth a combined $141M — down 85% from $929M a quarter earlier.

Sellers outnumbered buyers: 60 funds closed out of AMLX and 25 opened new positions — a net loss of 35 holders — while 48 trimmed existing stakes and 56 added.

The largest buyer was Goldman Sachs, adding an estimated $22.1M. The largest seller was Morgan Stanley, cutting an estimated $47M.

  • 143 institutional investors held Amylyx Pharmaceuticals (AMLX) as of Q1 2024, down from 178 in Q4 2023.
  • Funds reported $141M of Amylyx Pharmaceuticals stock for Q1 2024, down 85% quarter-over-quarter.
  • 25 funds opened new Amylyx Pharmaceuticals positions in Q1 2024 and 60 closed out, a net change of -35 holders.
  • The largest Amylyx Pharmaceuticals buyer in Q1 2024 was Goldman Sachs, an estimated $22.1M added.
  • The largest Amylyx Pharmaceuticals seller in Q1 2024 was Morgan Stanley, an estimated $47M sold.

Based on aggregated 13F filings for Q1 2024.