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Amylyx Pharmaceuticals

133 hedge funds and large institutions have $1.79B invested in Amylyx Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 47 funds opening new positions, 49 increasing their positions, 32 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

488% more first-time investments, than exits

New positions opened: 47 | Existing positions closed: 8

72% more capital invested

Capital invested by funds: $1.05B → $1.79B (+$748M)

53% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 32

40% more funds holding

Funds holding: 95133 (+38)

9.64% more ownership

Funds ownership: 63.67%73.31% (+9.6%)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

30% less call options, than puts

Call options by funds: $25M | Put options by funds: $35.5M

Holders
133
Holders Change
+38
Holders Change %
+40%
% of All Funds
2.14%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.08%
New
47
Increased
49
Reduced
32
Closed
8
Calls
$25M
Puts
$35.5M
Net Calls
-$10.6M
Net Calls Change
-$45.2M
Name Holding Trade Value Shares
Change
Change in
Stake
PA
1
Perceptive Advisors
New York
$225M +$21.9M +616,300 +11%
Viking Global Investors
2
Viking Global Investors
Connecticut
$171M -$40.3M -1,135,930 -20%
Vanguard Group
3
Vanguard Group
Pennsylvania
$161M +$30M +844,136 +24%
BlackRock
4
BlackRock
New York
$134M +$46.9M +1,321,092 +58%
DM
5
Deerfield Management
New York
$99.5M +$95.6M +2,693,000 New
Point72 Asset Management
6
Point72 Asset Management
Connecticut
$78.6M +$58.9M +1,660,999 +356%
BC
7
Boxer Capital
California
$77M
Adage Capital Partners
8
Adage Capital Partners
Massachusetts
$70.5M +$19.8M +559,201 +41%
Federated Hermes
9
Federated Hermes
Pennsylvania
$59.7M +$10.1M +285,845 +22%
D.E. Shaw & Co
10
D.E. Shaw & Co
New York
$51.1M +$43.3M +1,221,467 +753%
RSCM
11
Rock Springs Capital Management
Maryland
$45.4M +$29.3M +825,900 +205%
PAMS
12
Pictet Asset Management (Switzerland)
Switzerland
$41.4M +$39.8M +1,121,765 New
State Street
13
State Street
Massachusetts
$39.7M +$8.82M +248,544 +30%
Goldman Sachs
14
Goldman Sachs
New York
$38.3M +$23.3M +656,871 +173%
Millennium Management
15
Millennium Management
New York
$31.8M -$2.19M -61,713 -7%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$31.6M +$7.75M +218,357 +34%
EA
17
Emerald Advisers
Pennsylvania
$30.9M +$8.36M +235,683 +39%
AWG
18
Alpha Wave Global
New York
$30.3M +$4.28M +120,585 +17%
EMFAT
19
Emerald Mutual Fund Advisers Trust
Pennsylvania
$24.2M +$6.5M +183,128 +39%
Balyasny Asset Management
20
Balyasny Asset Management
Illinois
$23.9M +$16.1M +454,219 +237%
ACA
21
Avoro Capital Advisors
New York
$23.3M -$710K -20,000 -3%
N
22
Nuveen
North Carolina
$22M +$8.49M +239,367 +67%
CAM
23
Cormorant Asset Management
Massachusetts
$20.3M -$2.13M -60,000 -10%
WP
24
Woodline Partners
California
$18.8M -$18.2M -512,031 -50%
Morgan Stanley
25
Morgan Stanley
New York
$17.9M +$7.64M +215,399 +80%

AMLX Hedge Fund Activity: Q4 2022 in Review

133 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Amylyx Pharmaceuticals (AMLX) for Q4 2022, worth a combined $1.79B — up 72% from $1.05B a quarter earlier.

Buyers outnumbered sellers: 47 funds opened new AMLX positions and 8 closed out — a net gain of 39 holders — while 49 added to existing stakes and 32 trimmed.

The largest buyer was Deerfield Management, opening a new position worth an estimated $95.6M. The largest seller was Viking Global Investors, cutting an estimated $40.3M.

  • 133 institutional investors held Amylyx Pharmaceuticals (AMLX) as of Q4 2022, up from 95 in Q3 2022.
  • Funds reported $1.79B of Amylyx Pharmaceuticals stock for Q4 2022, up 72% quarter-over-quarter.
  • 47 funds opened new Amylyx Pharmaceuticals positions in Q4 2022 and 8 closed out, a net change of +39 holders.
  • The largest Amylyx Pharmaceuticals buyer in Q4 2022 was Deerfield Management, an estimated $95.6M added.
  • The largest Amylyx Pharmaceuticals seller in Q4 2022 was Viking Global Investors, an estimated $40.3M sold.

Based on aggregated 13F filings for Q4 2022.