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Amylyx Pharmaceuticals
AMLX

Overview Fund Activity

130 hedge funds and large institutions have $524M invested in Amylyx Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 37 increasing their positions, 37 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
130
Holders Change
-4
Holders Change %
-2.99%
% of All Funds
1.74%
Holding in Top 10
6
Holding in Top 10 Change
+5
Holding in Top 10 Change %
+500%
% of All Funds
0.08%
New
32
Increased
37
Reduced
37
Closed
36
Calls
$1.48M
Puts
$103K
Net Calls
+$1.38M
Net Calls Change
+$1.46M

Top Buyers

1
Point72 Asset Management
1
Point72 Asset Management
Connecticut
$29.1M
2
BlackRock
2
BlackRock
New York
$35.3M
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$56.4M
4
Fidelity Investments
4
Fidelity Investments
Massachusetts
$19.5M
5
DCM
5
Driehaus Capital Management
Illinois
$8.11M

Top Sellers

1
Aberdeen Group
1
Aberdeen Group
United Kingdom
$4.73M
2
Millennium Management
2
Millennium Management
New York
$9.69M
3
Citadel Advisors
3
Citadel Advisors
Florida
$7.97M
4
Susquehanna International Group
4
Susquehanna International Group
Pennsylvania
$711K
5
Goldman Sachs
5
Goldman Sachs
New York
$8.32M
Name Holding Trade Value Shares
Change 		Shares
Change %
SIC
126
Salem Investment Counselors
North Carolina
$353 – – –
PNC Financial Services Group
127
PNC Financial Services Group
Pennsylvania
$340 – – –
BIG
128
Brooklyn Investment Group
New York
$270 +$270 +42 New
EWA
129
EverSource Wealth Advisors
Alabama
$160 – – –
SS
130
SBI Securities
Japan
$6 – – –
Alyeska Investment Group
131
Alyeska Investment Group
Illinois
– -$2.66M -750,412 Closed
Walleye Capital
132
Walleye Capital
New York
– -$888K -250,888 Closed
Marshall Wace
133
Marshall Wace
United Kingdom
– -$875K -247,275 Closed
OAC
134
OMERS Administration Corp
Ontario, Canada
– -$600K -169,600 Closed
Balyasny Asset Management
135
Balyasny Asset Management
Illinois
– -$526K -148,559 Closed
HF
136
HRT Financial
New York
– -$453K -127,998 Closed
Man Group
137
Man Group
United Kingdom
– -$309K -87,352 Closed
Jacobs Levy Equity Management
138
Jacobs Levy Equity Management
New Jersey
– -$273K -77,091 Closed
JG
139
Jain Global
New York
– -$262K -73,942 Closed
AA
140
ALPS Advisors
Colorado
– -$239K -67,597 Closed
ECM
141
ExodusPoint Capital Management
New York
– -$211K -59,491 Closed
AG
142
Algert Global
California
– -$202K -57,133 Closed
JFG
143
Jefferies Financial Group
New York
– -$164K -46,200 Closed
LP
144
LMR Partners
United Kingdom
– -$153K -43,228 Closed
PAS
145
Point72 Asia (Singapore)
Singapore
– -$153K -43,200 Closed
QC
146
Quantessence Capital
New York
– -$142K -40,134 Closed
XT
147
XTX Topco
Cayman Islands
– -$140K -39,542 Closed
CGIM
148
Cannon Global Investment Management
Florida
– -$90.3K -25,500 Closed
SG Americas Securities
149
SG Americas Securities
New York
– -$89K -25,210 Closed
Verition Fund Management
150
Verition Fund Management
Connecticut
– -$85K -24,013 Closed
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