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Amylyx Pharmaceuticals
AMLX

Overview Fund Activity

129 hedge funds and large institutions have $523M invested in Amylyx Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 37 increasing their positions, 36 reducing their positions, and 36 closing their positions.

Holders
129
Holders Change
-5
Holders Change %
-3.73%
% of All Funds
1.73%
Holding in Top 10
6
Holding in Top 10 Change
+5
Holding in Top 10 Change %
+500%
% of All Funds
0.08%
New
32
Increased
37
Reduced
36
Closed
36
Calls
$568K
Puts
$17K
Net Calls
+$551K
Net Calls Change
+$633K

Top Buyers

1
Point72 Asset Management
1
Point72 Asset Management
Connecticut
$29.1M
2
BlackRock
2
BlackRock
New York
$35.3M
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$56.4M
4
Fidelity Investments
4
Fidelity Investments
Massachusetts
$19.5M
5
DCM
5
Driehaus Capital Management
Illinois
$8.11M

Top Sellers

1
Aberdeen Group
1
Aberdeen Group
United Kingdom
$4.73M
2
Millennium Management
2
Millennium Management
New York
$9.69M
3
Citadel Advisors
3
Citadel Advisors
Florida
$7.97M
4
Goldman Sachs
4
Goldman Sachs
New York
$8.32M
5
BCM
5
Boxer Capital Management
California
$7.85M
Name Market Value Shares Shares
Change 		Shares
Change %
PP
151
Paloma Partners
Connecticut
– – -22,242 Closed
Capstone Investment Advisors
152
Capstone Investment Advisors
New York
– – -16,150 Closed
SOW
153
State of Wyoming
Wyoming
– – -15,920 Closed
CFM
154
Catalyst Funds Management
Australia
– – -14,905 Closed
HSBC Holdings
155
HSBC Holdings
United Kingdom
– – -14,419 Closed
EGM
156
Engineers Gate Manager
New York
– – -13,382 Closed
TSS
157
Two Sigma Securities
New York
– – -13,301 Closed
RS
158
R Squared
Hong Kong
– – -12,736 Closed
BHCM
159
Brevan Howard Capital Management
Jersey
– – -11,330 Closed
CM
160
Capula Management
Cayman Islands
– – -10,980 Closed
EC
161
EntryPoint Capital
New York
– – -10,587 Closed
Hudson Bay Capital Management
162
Hudson Bay Capital Management
Connecticut
– – -10,340 Closed
PD
163
Point72 (DIFC)
United Arab Emirates
– – -5,047 Closed
Simplex Trading
164
Simplex Trading
Illinois
– – -4,162 Closed
AAM
165
Advisors Asset Management
Colorado
– – -2,573 Closed
CCM
166
Coldstream Capital Management
Washington
– – -238 Closed
3 4 5 6
7