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Amylyx Pharmaceuticals

178 hedge funds and large institutions have $1.36B invested in Amylyx Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 40 funds opening new positions, 70 increasing their positions, 44 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

9% less capital invested

Capital invested by funds: $1.49B → $1.36B (-$135M)

20.81% less ownership

Funds ownership: 123.05%102.24% (-21%)

33% less funds holding in top 10

Funds holding in top 10: 96 (-3)

Holders
178
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$6.39M
Puts
$1.21M
Net Calls
Net Calls Change

Top Buyers

1 +$69.8M
2 +$26.2M
3 +$26M
4
CC
Commodore Capital
New York
+$21.4M
5
Franklin Resources
Franklin Resources
California
+$16.3M
Name Holding Trade Value Shares
Change
Change in
Stake
SCM
151
Sterling Capital Management
North Carolina
$19.7K
SPIA
152
Steward Partners Investment Advisory
New York
$18.1K
SOW
153
State of Wyoming
Wyoming
$16.7K
BNP Paribas Asset Management
154
BNP Paribas Asset Management
France
$16K
Carson Wealth (CWM LLC)
155
Carson Wealth (CWM LLC)
Nebraska
$14K
Los Angeles Capital Management
156
Los Angeles Capital Management
California
$12K
Nisa Investment Advisors
157
Nisa Investment Advisors
Missouri
$11.1K
WA
158
Westfuller Advisors
New York
$9.89K
DF
159
Dunhill Financial
United Kingdom
$7.25K
PNC Financial Services Group
160
PNC Financial Services Group
Pennsylvania
$5.29K
PWA
161
Physician Wealth Advisors
Utah
$3.31K
GI
162
GAMMA Investing
California
$3.23K
Rockefeller Capital Management
163
Rockefeller Capital Management
New York
$3.15K
Osaic Holdings
164
Osaic Holdings
Arizona
$3.01K
Daiwa Securities Group
165
Daiwa Securities Group
Japan
$3K
EWM
166
Evolution Wealth Management
Florida
$1.99K
MPWT
167
MassMutual Private Wealth & Trust
Connecticut
$1.85K
JSAM
168
J. Safra Asset Management
New York
$1.49K
HI
169
Harbour Investments
Wisconsin
$1.09K
CAIM
170
Catherine Avery Investment Management
Florida
$1.05K
LFG
171
Larson Financial Group
Missouri
$495
Jones Financial Companies
172
Jones Financial Companies
Missouri
$362
FC
173
Financial Consulate
Maryland
$302
EWA
174
EverSource Wealth Advisors
Alabama
$302
FFA
175
Farther Finance Advisors
California
$242