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UPB

Woodline Partners’s Upstream Bio Inc UPB Stock Holding History

Woodline Partners’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$5.75M Hold
831,481
– – 0.02% 657
2026
Q1 		$7.48M Buy
831,481
+71,229
+9% +$1.28M 0.03% 579
2025
Q4 		$20.6M Buy
760,252
+158,000
+26% +$3.93M 0.08% 305
2025
Q3 		$11.3M Buy
602,252
+44,000
+8% +$684K 0.05% 415
2025
Q2 		$6.13M Buy
558,252
+1,189
+0.2% +$11K 0.03% 523
2025
Q1 		$3.41M Buy
557,063
+30,552
+6% +$292K 0.02% 589
2024
Q4 		$8.66M Buy
+526,511
New +$11.8M 0.06% 379

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Woodline Partners's UPB Position: Q2 2026 in Review

Woodline Partners held its Upstream Bio Inc (UPB) position steady in Q2 2026 at 831,481 shares worth $5.75M. The position accounts for 0.02% of the portfolio, ranked #657.

Woodline Partners first reported a position in UPB in Q4 2024 and has held it in 7 quarters since. The position peaked at $20.6M in Q4 2025. 148 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Woodline Partners held 831,481 shares of Upstream Bio Inc worth $5.75M as of Q2 2026.
  • Woodline Partners left its Upstream Bio Inc share count unchanged in Q2 2026.
  • Upstream Bio Inc made up 0.02% of Woodline Partners's portfolio in Q2 2026, its #657 holding.
  • Woodline Partners first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 7 quarters since.
  • Woodline Partners's Upstream Bio Inc position peaked at $20.6M in Q4 2025.
  • 148 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Woodline Partners's 13F filing for Q2 2026, filed 14 Aug 2026.