Two Sigma Securities’s State Street SPDR S&P Biotech ETF XBI Stock Holding History

Two Sigma Securities’s Portfolio XBI Stock Details XBI Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2024 Q4	–	Sell	-17,500	Closed	-$1.73M	–	3357
2024 Q3	$1.73M	Sell	17,500 -5,300	-23%	-$521K	0.03%	609
2024 Q2	$2.11M	Sell	22,800 -500	-2%	-$44.8K	0.03%	687
2024 Q1	$2.21M	Sell	23,300 -31,800	-58%	-$2.95M	0.02%	711
2023 Q4	$4.92M	Sell	55,100 -16,600	-23%	-$1.23M	0.05%	366
2023 Q3	$5.24M	Buy	71,700 +53,400	+292%	+$4.27M	0.06%	354
2023 Q2	$1.52M	Sell	18,300 -1,600	-8%	-$134K	0.02%	734
2023 Q1	$1.52M	Sell	19,900 -44,400	-69%	-$3.68M	0.03%	641
2022 Q4	$5.34M	Buy	64,300 +42,000	+188%	+$3.4M	0.16%	137
2022 Q3	$1.77M	Buy	22,300 +16,500	+284%	+$1.39M	0.05%	402
2022 Q2	$431K	Buy	5,800 +2,900	+100%	+$218K	0.02%	1015
2022 Q1	$261K	Sell	2,900 -3,800	-57%	-$351K	0.01%	1520
2021 Q4	$750K	Sell	6,700 -39,000	-85%	-$4.7M	0.03%	360
2021 Q3	$5.75M	Buy	45,700 +13,900	+44%	+$1.79M	0.17%	96
2021 Q2	$4.31M	Buy	+31,800	New	+$4.18M	0.13%	103
2021 Q1	–	Sell	-24,000	Closed	-$3.38M	–	1831
2020 Q4	$3.38M	Buy	24,000 +8,700	+57%	+$1.11M	0.08%	156
2020 Q3	$1.71M	Sell	15,300 -28,800	-65%	-$3.23M	0.03%	237
2020 Q2	$4.94M	Buy	44,100 +12,000	+37%	+$1.18M	0.11%	98
2020 Q1	$2.49M	Sell	32,100 -185,500	-85%	-$16.4M	0.06%	215
2019 Q4	$20.7M	Buy	217,600 +139,300	+178%	+$12M	0.14%	95
2019 Q3	$5.97M	Sell	78,300 -31,900	-29%	-$2.65M	0.05%	276
2019 Q2	$9.67M	Buy	110,200 +107,800	+4,492%	+$9.19M	0.1%	115
2019 Q1	$217K	Sell	2,400 -32,800	-93%	-$2.79M	﹤0.01%	1426
2018 Q4	$2.53M	Sell	35,200 -95,100	-73%	-$7.66M	0.03%	292
2018 Q3	$12.5M	Sell	130,300 -189,100	-59%	-$18.3M	0.08%	168
2018 Q2	$30.4M	Buy	319,400 +69,100	+28%	+$6.35M	0.15%	95
2018 Q1	$22M	Buy	250,300 +181,400	+263%	+$16.6M	0.12%	139
2017 Q4	$5.85M	Buy	+68,900	New	+$5.77M	0.16%	102

Other funds holding XBI

BNP Paribas Financial Markets Paris, France $289B AUM 60.46% 1-Year Est. Return

Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return

Citigroup New York $303B AUM 53.02% 1-Year Est. Return

Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return

Bank of America Charlotte, North Carolina $1.55T AUM 33.47% 1-Year Est. Return

Healthcare of Ontario Pension Plan (HOOPP) Trust Fund Toronto, Ontario, Canada $71.2B AUM 48.86% 1-Year Est. Return

Wells Fargo San Francisco, California $617B AUM 30.33% 1-Year Est. Return

UBS Group Zurich, Switzerland $786B AUM 40.34% 1-Year Est. Return

Barclays London, United Kingdom $521B AUM 51.41% 1-Year Est. Return

JFG

Jefferies Financial Group New York $15.2B AUM 55.75% 1-Year Est. Return

Two Sigma Securities's XBI Position: Q2 2026 in Review

Two Sigma Securities opened a new position in State Street SPDR S&P Biotech ETF (XBI) in Q2 2026: 3,610 shares worth $571K. The stake represents 0.05% of the portfolio and ranks #520 among its holdings. This is a return to the name: Two Sigma Securities previously reported a position in XBI as recently as Q3 2025.

Two Sigma Securities first reported a position in XBI in Q1 2015 and has held it in 27 quarters since. The position peaked at $10.2M in Q1 2017. 933 funds tracked by Wall St. Rank hold XBI as of Q2 2026.

Two Sigma Securities held 3,610 shares of State Street SPDR S&P Biotech ETF worth $571K as of Q2 2026.
State Street SPDR S&P Biotech ETF was a new Two Sigma Securities position in Q2 2026.
State Street SPDR S&P Biotech ETF made up 0.05% of Two Sigma Securities's portfolio in Q2 2026, its #520 holding.
Two Sigma Securities first reported a position in State Street SPDR S&P Biotech ETF in Q1 2015 and has held it in 27 quarters since.
Two Sigma Securities's State Street SPDR S&P Biotech ETF position peaked at $10.2M in Q1 2017.
933 funds tracked by Wall St. Rank held State Street SPDR S&P Biotech ETF as of Q2 2026.

Based on Two Sigma Securities's 13F filing for Q2 2026, filed 14 Aug 2026.