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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
+16.87%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$493M
AUM Growth
+$4.13M
Cap. Flow
-$34.1M
Cap. Flow %
-6.93%
Top 10 Hldgs %
38.08%
Holding
111
New
22
Increased
19
Reduced
35
Closed
22

Top Buys

Rank Stock Value
1
CNC icon
Centene
CNC
+$13.5M
2
CI icon
Cigna
CI
+$9.96M
3
MRK icon
Merck
MRK
+$9.66M
4
ICLR icon
Icon
ICLR
+$9.38M
5
GSK icon
GSK
GSK
+$9.35M

Top Sells

Rank Stock Value
1
AZN icon
AstraZeneca
AZN
+$13.1M
2
COR icon
Cencora
COR
+$12.5M
3
WBA
Walgreens Boots Alliance
WBA
+$12.3M
4
SNY icon
Sanofi
SNY
+$10.7M
5
AMGN icon
Amgen
AMGN
+$9.2M

Sector Composition

Rank Sector Weight
1 Healthcare 87.45%
2 Consumer Staples 1.34%
3 Technology 0.67%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
OFIX icon
101
Orthofix Medical
OFIX
$428M
-138,525
Closed -$5.95M
OTRK
102
DELISTED
Ontrak
OTRK
-425
Closed -$2.36M
SNY icon
103
Sanofi
SNY
$104B
-220,201
Closed -$10.7M
VREX icon
104
Varex Imaging
VREX
$516M
-266,740
Closed -$4.45M
WBA
105
DELISTED
Walgreens Boots Alliance
WBA
-308,686
Closed -$12.3M
VRAY
106
DELISTED
ViewRay, Inc.
VRAY
-775,000
Closed -$2.96M
ZSAN
107
DELISTED
Zosano Pharma Corporation
ZSAN
-12,215
Closed -$225K
ODT
108
DELISTED
Odonate Therapeutics, Inc. Common Stock
ODT
-75,500
Closed -$1.45M
CHAQ.U
109
DELISTED
Chardan Healthcare Acquisition 2 Corp. Units, each consisting of one share of Common Stock, and one
CHAQ.U
-400,000
Closed -$4.24M
VINCW
110
DELISTED
Vincerx Pharma, Inc. Warrant
VINCW
-210,000
Closed -$693K
GWPH
111
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
-33,801
Closed -$3.9M

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Sio Capital Management's Q1 2021 Portfolio in Review

As of Q1 2021, Sio Capital Management held 111 positions worth $493M, up 0.85% from $489M the previous quarter. Its ten largest holdings account for 38% of the portfolio.

Sio Capital Management withdrew a net $34.1M in Q1 2021, closing 22 positions and reducing 35 holdings. Its most notable exit was AstraZeneca, an estimated $13.1M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 87% of assets, up from 82% a quarter earlier, followed by Consumer Staples and Technology.

Against the trend, Sio Capital Management opened a new position in Centene worth $13.9M.

  • Sio Capital Management's largest Q1 2021 buy was Centene: 217,500 shares worth $13.9M.
  • Sio Capital Management added most to Cigna in Q1 2021, an estimated $9.96M increase.
  • Sio Capital Management's biggest Q1 2021 reduction was Curis, cutting an estimated $3.92M.
  • Sio Capital Management fully exited AstraZeneca in Q1 2021, selling an estimated $13.1M.
  • Sio Capital Management's ten largest holdings make up 38% of its $493M portfolio in Q1 2021.
  • Sio Capital Management opened 22 new positions and closed 22 in Q1 2021.
  • Sio Capital Management's portfolio value rose 0.85% quarter-over-quarter to $493M.

Based on Sio Capital Management's 13F filing for Q1 2021, filed 14 May 2021.