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Sio Capital Management Portfolio holdings

AUM $604M
1-Year Est. Return 96.57%
This Fund
S&P 500
This Quarter Est. Return
-3.76%
1 Year Est. Return
+96.57%
3 Year Est. Return
+564.25%
5 Year Est. Return
+486.18%
10 Year Est. Return
+2,856.71%
AUM
$302M
AUM Growth
-$29.4M
Cap. Flow
-$60.3M
Cap. Flow %
-19.96%
Top 10 Hldgs %
56.17%
Holding
86
New
16
Increased
11
Reduced
16
Closed
20

Top Buys

Rank Stock Value
1
LH icon
Labcorp
LH
+$13.5M
2
SNY icon
Sanofi
SNY
+$10.9M
3
INGN icon
Inogen
INGN
+$9.8M
4
VREX icon
Varex Imaging
VREX
+$8.02M
5
MEDP icon
Medpace
MEDP
+$4.68M

Top Sells

Rank Stock Value
1
CAH icon
Cardinal Health
CAH
+$17.3M
2
GLD icon
SPDR Gold Trust
GLD
+$15.4M
3
CI icon
Cigna
CI
+$12.5M
4
HLF icon
Herbalife
HLF
+$9.88M
5
LKFT
Lakefront Biotherapeutics American Depositary Shares
LKFT
+$7.02M

Sector Composition

Rank Sector Weight
1 Healthcare 73.21%
2 Miscellaneous 18.84%
3 Financials 7.52%
4 Industrials 0.43%
5 Consumer Staples 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
VRTX icon
1
PUT
Vertex Pharmaceuticals
VRTX
$137B
$34.7M 11.48%
+133,000
New +$31.6M
MSAC
2
DELISTED
Medicus Sciences Acquisition Corp. Class A Ordinary Share
MSAC
$22.7M 7.52%
2,323,000
– –
CI icon
3
Cigna
CI
$73.7B
$16.3M 5.38%
67,830
-53,500
-44% -$12.5M
MRK icon
4
Merck
MRK
$366B
$16M 5.3%
195,160
-38,501
-16% -$3.04M
SNY icon
5
Sanofi
SNY
$107B
$15.4M 5.1%
300,000
+211,751
+240% +$10.9M
VRTX icon
6
CALL
Vertex Pharmaceuticals
VRTX
$137B
$15.3M 5.05%
+58,500
New +$13.9M
LH icon
7
Labcorp
LH
$27.2B
$13M 4.3%
+57,418
New +$13.5M
INGN icon
8
Inogen
INGN
$146M
$13M 4.29%
400,086
+311,795
+353% +$9.8M
COR icon
9
Cencora
COR
$61.5B
$12.9M 4.26%
83,271
-14,169
-15% -$2.01M
MCK icon
10
McKesson
MCK
$104B
$10.6M 3.49%
34,501
-22,555
-40% -$6.13M
UTHR icon
11
United Therapeutics
UTHR
$22.1B
$9.91M 3.28%
55,262
+2,069
+4% +$394K
LKFT
12
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.89B
$9.1M 3.01%
146,696
-114,681
-44% -$7.02M
CNC icon
13
Centene
CNC
$32B
$8.15M 2.69%
96,762
-29,017
-23% -$2.38M
VREX icon
14
Varex Imaging
VREX
$780M
$6.72M 2.22%
+315,486
New +$8.02M
IONS icon
15
Ionis Pharmaceuticals
IONS
$10.1B
$6.5M 2.15%
175,568
-146,998
-46% -$4.81M
NTUS
16
DELISTED
Natus Medical Inc
NTUS
$5.03M 1.67%
191,564
+83,869
+78% +$2.05M
VAPO
17
DELISTED
Vapotherm, Inc. Common Stock
VAPO
$4.91M 1.62%
44,126
+21,624
+96% +$2.7M
MEDP icon
18
Medpace
MEDP
$16.8B
$4.65M 1.54%
+28,400
New +$4.68M
CRIS icon
19
Curis
CRIS
$3.61M
$4.56M 1.51%
4,789
-4,878
-50% -$6.23M
ALBO
20
DELISTED
Albireo Pharma Inc
ALBO
$4.31M 1.43%
144,546
-69,367
-32% -$2.03M
NKTR icon
21
PUT
Nektar Therapeutics
NKTR
$2.48B
$3.74M 1.24%
+46,247
New +$6.84M
NARI
22
DELISTED
Inari Medical, Inc. Common Stock
NARI
$3.65M 1.21%
+40,210
New +$3.29M
MIRM icon
23
Mirum Pharmaceuticals
MIRM
$5.94B
$3.55M 1.17%
161,285
-109,029
-40% -$2.22M
XENE icon
24
Xenon Pharmaceuticals
XENE
$5.81B
$3.23M 1.07%
+105,756
New +$3.17M
RCOR
25
DELISTED
Renovacor, Inc.
RCOR
$3.12M 1.03%
735,908
– –
1
2 3 4

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V
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MAM
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RCM
Requisite Capital Management Dallas, Texas $605M AUM 17.2% 1-Year Est. Return
AMG
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VV
Verbena Value Westport, Connecticut $605M AUM
VCP
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EHI
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Sio Capital Management's Q1 2022 Portfolio in Review

As of Q1 2022, Sio Capital Management held 86 positions worth $302M, down 8.9% from $332M the previous quarter. Its ten largest holdings account for 56% of the portfolio.

Sio Capital Management withdrew a net $60.3M in Q1 2022, closing 20 positions and reducing 16 holdings. Its most notable exit was Cardinal Health, an estimated $17.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 73% of assets, down from 83% a quarter earlier, followed by Miscellaneous and Financials.

Against the trend, Sio Capital Management opened a new position in Labcorp worth $13M.

  • Sio Capital Management's largest Q1 2022 buy was Labcorp: 57,418 shares worth $13M.
  • Sio Capital Management added most to Sanofi in Q1 2022, an estimated $10.9M increase.
  • Sio Capital Management's biggest Q1 2022 reduction was Cigna, cutting an estimated $12.5M.
  • Sio Capital Management fully exited Cardinal Health in Q1 2022, selling an estimated $17.3M.
  • Sio Capital Management's ten largest holdings make up 56% of its $302M portfolio in Q1 2022.
  • Sio Capital Management opened 16 new positions and closed 20 in Q1 2022.
  • Sio Capital Management's portfolio value fell 8.9% quarter-over-quarter to $302M.

Based on Sio Capital Management's 13F filing for Q1 2022, filed 16 May 2022.