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Sio Capital Management Portfolio holdings

AUM $604M
1-Year Est. Return 96.57%
This Fund
S&P 500
This Quarter Est. Return
-3.76%
1 Year Est. Return
+96.57%
3 Year Est. Return
+564.25%
5 Year Est. Return
+486.18%
10 Year Est. Return
+2,856.71%
AUM
$302M
AUM Growth
-$29.4M
Cap. Flow
-$60.3M
Cap. Flow %
-19.96%
Top 10 Hldgs %
56.17%
Holding
86
New
16
Increased
11
Reduced
16
Closed
20
Avg Time Held Equity + Options
3 quarters
Top 10 Avg Time Held Equity + Options
0.9 quarters
Top 20 Avg Time Held Equity + Options
1.8 quarters
Avg Time Held Equity only
3.2 quarters
Top 10 Avg Time Held Equity only
1.3 quarters
Top 20 Avg Time Held Equity only
1.8 quarters

Top Buys

Rank Stock Value
1
LH icon
Labcorp
LH
+$13.5M
2
SNY icon
Sanofi
SNY
+$10.9M
3
INGN icon
Inogen
INGN
+$9.8M
4
VREX icon
Varex Imaging
VREX
+$8.02M
5
MEDP icon
Medpace
MEDP
+$4.68M

Sector Composition

Rank Sector Weight
1 Healthcare 73.21%
2 Miscellaneous 18.84%
3 Financials 7.52%
4 Industrials 0.43%
5 Consumer Staples 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
VRTX icon
1
PUT
Vertex Pharmaceuticals
VRTX
$123B
$34.7M 11.48%
+133,000
New +$31.6M
2022 Q1
0 quarters
MSAC
2
DELISTED
Medicus Sciences Acquisition Corp. Class A Ordinary Share
MSAC
$22.7M 7.52%
2,323,000
– –
2021 Q4
1 quarter
CI icon
3
Cigna
CI
$74.7B
$16.3M 5.38%
67,830
-53,500
-44% -$12.5M
2020 Q3
6 quarters
MRK icon
4
Merck
MRK
$350B
$16M 5.3%
195,160
-38,501
-16% -$3.04M
2021 Q3
2 quarters
SNY icon
5
Sanofi
SNY
$93.7B
$15.4M 5.1%
300,000
+211,751
+240% +$10.9M
2021 Q4
1 quarter
VRTX icon
6
CALL
Vertex Pharmaceuticals
VRTX
$123B
$15.3M 5.05%
+58,500
New +$13.9M
2022 Q1
0 quarters
LH icon
7
Labcorp
LH
$25.4B
$13M 4.3%
+57,418
New +$13.5M
2022 Q1
0 quarters
INGN icon
8
Inogen
INGN
$168M
$13M 4.29%
400,086
+311,795
+353% +$9.8M
2021 Q4
1 quarter
COR icon
9
Cencora
COR
$63B
$12.9M 4.26%
83,271
-14,169
-15% -$2.01M
2021 Q4
1 quarter
MCK icon
10
McKesson
MCK
$112B
$10.6M 3.49%
34,501
-22,555
-40% -$6.13M
2019 Q3
10 quarters
UTHR icon
11
United Therapeutics
UTHR
$23.3B
$9.91M 3.28%
55,262
+2,069
+4% +$394K
2018 Q4
13 quarters
LKFT icon
12
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.9B
$9.1M 3.01%
146,696
-114,681
-44% -$7.02M
2021 Q3
2 quarters
CNC icon
13
Centene
CNC
$34B
$8.15M 2.69%
96,762
-29,017
-23% -$2.38M
2021 Q1
4 quarters
VREX icon
14
Varex Imaging
VREX
$784M
$6.72M 2.22%
+315,486
New +$8.02M
2022 Q1
0 quarters
IONS icon
15
Ionis Pharmaceuticals
IONS
$7.04B
$6.5M 2.15%
175,568
-146,998
-46% -$4.81M
2021 Q4
1 quarter
NTUS
16
DELISTED
Natus Medical Inc
NTUS
$5.03M 1.67%
191,564
+83,869
+78% +$2.05M
2021 Q3
2 quarters
VAPO
17
DELISTED
Vapotherm, Inc. Common Stock
VAPO
$4.91M 1.62%
44,126
+21,624
+96% +$2.7M
2021 Q4
1 quarter
MEDP icon
18
Medpace
MEDP
$17B
$4.65M 1.54%
+28,400
New +$4.68M
2022 Q1
0 quarters
CRIS icon
19
Curis
CRIS
$1.49M
$4.56M 1.51%
4,789
-4,878
-50% -$6.23M
2020 Q2
7 quarters
ALBO
20
DELISTED
Albireo Pharma Inc
ALBO
$4.31M 1.43%
144,546
-69,367
-32% -$2.03M
2020 Q3
6 quarters
NKTR icon
21
PUT
Nektar Therapeutics
NKTR
$1.29B
$3.74M 1.24%
+46,247
New +$6.84M
2022 Q1
0 quarters
NARI icon
22
DELISTED
Inari Medical, Inc. Common Stock
NARI
$3.65M 1.21%
+40,210
New +$3.29M
2022 Q1
0 quarters
MIRM icon
23
Mirum Pharmaceuticals
MIRM
$5.17B
$3.55M 1.17%
161,285
-109,029
-40% -$2.22M
2020 Q4
5 quarters
XENE icon
24
Xenon Pharmaceuticals
XENE
$3.33B
$3.23M 1.07%
+105,756
New +$3.17M
2022 Q1
0 quarters
RCOR
25
DELISTED
Renovacor, Inc.
RCOR
$3.12M 1.03%
735,908
– –
2021 Q1
4 quarters

Similar funds

Sio Capital Management's Q1 2022 Portfolio in Review

As of Q1 2022, Sio Capital Management held 86 positions worth $302M, down 8.9% from $332M the previous quarter. Its ten largest holdings account for 56% of the portfolio.

Sio Capital Management withdrew a net $60.3M in Q1 2022, closing 20 positions and reducing 16 holdings. Its most notable exit was Cardinal Health, an estimated $17.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 73% of assets, down from 83% a quarter earlier, followed by Miscellaneous and Financials.

Against the trend, Sio Capital Management opened a new position in Labcorp worth $13M.

  • Sio Capital Management's largest Q1 2022 buy was Labcorp: 57,418 shares worth $13M.
  • Sio Capital Management added most to Sanofi in Q1 2022, an estimated $10.9M increase.
  • Sio Capital Management's biggest Q1 2022 reduction was Cigna, cutting an estimated $12.5M.
  • Sio Capital Management fully exited Cardinal Health in Q1 2022, selling an estimated $17.3M.
  • Sio Capital Management's ten largest holdings make up 56% of its $302M portfolio in Q1 2022.
  • Sio Capital Management opened 16 new positions and closed 20 in Q1 2022.
  • Sio Capital Management's portfolio value fell 8.9% quarter-over-quarter to $302M.

Based on Sio Capital Management's 13F filing for Q1 2022, filed 16 May 2022.