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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
+0.02%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$697M
AUM Growth
+$61.6M
Cap. Flow
+$92.3M
Cap. Flow %
13.24%
Top 10 Hldgs %
45.13%
Holding
90
New
22
Increased
24
Reduced
17
Closed
14

Top Buys

Rank Stock Value
1
COR icon
Cencora
COR
+$29.7M
2
WAY
Waystar Holding Corp
WAY
+$27.3M
3
CORT icon
Corcept Therapeutics
CORT
+$25.2M
4
ICLR icon
Icon
ICLR
+$24.5M
5
MMS icon
Maximus
MMS
+$21.8M

Top Sells

Rank Stock Value
1
CI icon
Cigna
CI
+$47.4M
2
SNY icon
Sanofi
SNY
+$34.1M
3
CELC icon
Celcuity
CELC
+$30.9M
4
ZBH icon
Zimmer Biomet
ZBH
+$29.6M
5
KVUE icon
Kenvue
KVUE
+$25.3M

Sector Composition

Rank Sector Weight
1 Healthcare 92.44%
2 Industrials 7.07%
3 Consumer Staples 0%

No holdings matched the selected filter criteria.

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Sio Capital Management's Q1 2026 Portfolio in Review

As of Q1 2026, Sio Capital Management held 90 positions worth $697M, up 9.7% from $636M the previous quarter. Its ten largest holdings account for 45% of the portfolio.

Sio Capital Management deployed $92.3M of net new capital in Q1 2026, opening 22 new positions and adding to 24 existing holdings. Its largest new stake was Corcept Therapeutics: 674,759 shares worth $27.2M.

By sector, the portfolio is most concentrated in Healthcare at 92% of assets, up from 84% a quarter earlier, followed by Industrials and Consumer Staples.

On the sell side, the largest reduction was Sanofi, an estimated $34.1M trimmed.

  • Sio Capital Management's largest Q1 2026 buy was Corcept Therapeutics: 674,759 shares worth $27.2M.
  • Sio Capital Management added most to Cencora in Q1 2026, an estimated $29.7M increase.
  • Sio Capital Management's biggest Q1 2026 reduction was Sanofi, cutting an estimated $34.1M.
  • Sio Capital Management fully exited Cigna in Q1 2026, selling an estimated $47.4M.
  • Sio Capital Management's ten largest holdings make up 45% of its $697M portfolio in Q1 2026.
  • Sio Capital Management opened 22 new positions and closed 14 in Q1 2026.
  • Sio Capital Management's portfolio value rose 9.7% quarter-over-quarter to $697M.

Based on Sio Capital Management's 13F filing for Q1 2026, filed 14 May 2026.