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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
-7.3%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$314M
AUM Growth
-$88.6M
Cap. Flow
-$54.8M
Cap. Flow %
-17.46%
Top 10 Hldgs %
50.02%
Holding
85
New
12
Increased
22
Reduced
16
Closed
24

Sector Composition

Rank Sector Weight
1 Healthcare 87.44%
2 Consumer Staples 2.92%
3 Industrials 0.71%
4 Financials 0.56%
5 Technology 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
MRSN
76
DELISTED
Mersana Therapeutics
MRSN
-6,290
Closed -$2.14M
PRQR icon
77
ProQR Therapeutics
PRQR
$278M
-380,045
Closed -$2.56M
SEER icon
78
Seer Inc
SEER
$121M
-23,775
Closed -$779K
TVTX icon
79
Travere Therapeutics
TVTX
$5.92B
-150,000
Closed -$2.19M
NARI
80
DELISTED
Inari Medical, Inc. Common Stock
NARI
-46,332
Closed -$4.32M
BCEL
81
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
-113,455
Closed -$967K
SYNH
82
DELISTED
Syneos Health, Inc. Class A Common Stock
SYNH
-62,598
Closed -$5.6M
HRC
83
DELISTED
HILL-ROM HOLDINGS, INC.
HRC
-76,647
Closed -$8.71M
CHAQ.U
84
DELISTED
Chardan Healthcare Acquisition 2 Corp. Units, each consisting of one share of Common Stock, and one
CHAQ.U
-400,000
Closed -$4.37M
AHACU
85
DELISTED
Alpha Healthcare Acquisition Corp Unit
AHACU
-100,000
Closed -$1.14M

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Sio Capital Management's Q3 2021 Portfolio in Review

As of Q3 2021, Sio Capital Management held 85 positions worth $314M, down 22% from $402M the previous quarter. Its ten largest holdings account for 50% of the portfolio.

Sio Capital Management withdrew a net $54.8M in Q3 2021, closing 24 positions and reducing 16 holdings. Its most notable exit was HILL-ROM HOLDINGS, INC., an estimated $8.71M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 87% of assets, up from 79% a quarter earlier, followed by Consumer Staples and Industrials.

Against the trend, Sio Capital Management opened a new position in Lakefront Biotherapeutics American Depositary Shares worth $11.8M.

  • Sio Capital Management's largest Q3 2021 buy was Lakefront Biotherapeutics American Depositary Shares: 224,719 shares worth $11.8M.
  • Sio Capital Management added most to Cigna in Q3 2021, an estimated $11.1M increase.
  • Sio Capital Management's biggest Q3 2021 reduction was Horizon Therapeutics Public Limited Company Ordinary Shares, cutting an estimated $3.96M.
  • Sio Capital Management fully exited HILL-ROM HOLDINGS, INC. in Q3 2021, selling an estimated $8.71M.
  • Sio Capital Management's ten largest holdings make up 50% of its $314M portfolio in Q3 2021.
  • Sio Capital Management opened 12 new positions and closed 24 in Q3 2021.
  • Sio Capital Management's portfolio value fell 22% quarter-over-quarter to $314M.

Based on Sio Capital Management's 13F filing for Q3 2021, filed 15 Nov 2021.